(S)-(−)-Sulpiride
(S)-(−)-Sulpiride (CAS: 23672-07-3, C15H23N3O4S) is a bioactive small molecule, classified as a dopaminergic antagonist. With a molecular weight of 341.43 g/mol, this compound is instrumental in neuroscientific research, particularly in studying dopamine receptor function and its role in cellular signaling pathways. It serves as a valuable reagent in cell biology and neuroscience laboratories for investigating neurotransmission.
- IUPAC
- (S)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide,Levosulpiride
- Synonyms
- (S)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide,Levosulpiride

Dopamine Receptor Studies
Used to investigate the functional role of dopamine D2 receptors in cellular processes and their impact on ion channel activity, such as KCNQ potassium channels.
Neuroscience Research
Employed in studies examining depression-like behaviours in animal models, specifically in relation to dopaminergic pathways and receptor function in ovariectomized female rats.
GPCR Modulation
Serves as a tool for researchers studying G protein-coupled receptors (GPCRs), specifically dopaminergic receptors, and their modulators.
| Molecular weight | 341.43 |
|---|---|
| Empirical formula | C15H23N3O4S |
| Assay | ≥98% (titration) |
| Storage temperature | 2-8°C |
| Application | (S)-(−)-Sulpiride was used to study the effect of dopamine D2 receptor function on activation of KCNQ potassium channels10 and on depression-like behavior in ovariectomized female rats.11 |
| Melting point | 183-186 °C(lit.) |
| Gene Information | human ... DRD2(1813), DRD3(1814)rat ... Adra1a(29412), Drd2(24318), Drd3(29238), Htr1a(24473), Htr2a(29595) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-Sulpiride used for?
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(S)-(−)-Sulpiride is primarily used in research to study dopamine D2 receptor function, its effects on potassium channels, and its role in depression-like behaviors. It is a valuable tool in neuroscience and cell biology research.
What are the CAS number and formula for (S)-(−)-Sulpiride?
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The CAS number for (S)-(−)-Sulpiride is 23672-07-3, and its empirical formula is C15H23N3O4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-Sulpiride with an assay of ≥98% (titration). TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for (S)-(−)-Sulpiride?
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(S)-(−)-Sulpiride is classified under WGK Germany 3, indicating it is hazardous to water. Appropriate handling procedures should be followed in a laboratory setting, avoiding release into the environment. Consult the Safety Data Sheet (SDS) for detailed information.
How is (S)-(−)-Sulpiride stored and shipped?
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(S)-(−)-Sulpiride should be stored at 2-8°C. As a global supplier, TSS ensures compliant packaging and export procedures for this chemical.
How can I request a quote or sample for (S)-(−)-Sulpiride?
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To request a quote or sample of (S)-(−)-Sulpiride, please contact our sales department through the TSS website or by calling our customer service line.
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