(Z)-4-Hydroxytamoxifen
(Z)-4-Hydroxytamoxifen (CAS 68047-06-3, C26H29NO2, MW 387.51) is a bioactive small molecule and a selective estrogen receptor modulator (SERM). It is recognized for its potential in research applications related to hormone-dependent cancers and cell signaling pathways. Supplied as a powder, this premium grade chemical is essential for advanced laboratory investigations.
- IUPAC
- (Z)-4-OHT,(Z)-4-(1-[4-(Dimethylaminoethoxy)phenyl]-2-phenyl-1-butenyl)phenol,trans-4-Hydroxytamoxifen
- Synonyms
- (Z)-4-OHT(Z)-4-(1-[4-(Dimethylaminoethoxy)phenyl]-2-phenyl-1-butenyl)phenoltrans-4-Hydroxytamoxifen
Endocrine Research
(Z)-4-Hydroxytamoxifen is utilized in studies investigating estrogen receptor activity and its role in various physiological processes. Its SERM properties make it valuable for understanding hormone signaling pathways.
Cancer Research
This compound is employed in preclinical research for its potential antineoplastic properties. Investigations often focus on its effects on hormone-dependent tumors and cellular proliferation.
Biochemical Assays
As a biochemical reagent, (Z)-4-Hydroxytamoxifen serves as a tool in a range of in vitro assays. It aids in the characterisation of receptor binding and cellular responses.
| Molecular weight | 387.51 |
|---|---|
| Empirical formula | C26H29NO2 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Solubility | methanol: soluble10 mg/mLethanol: soluble20 mg/mL (with heating) |
| Storage temperature | 2-8°C |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
- H361Suspected of damaging fertility or the unborn child
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 63-20/21/22 |
| Safety statements (S) | 22-23-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Quality Level | PREMIUM |
|---|---|
| Gene Information | human ... ESR1(2099), ESR2(2100), ESRRG(2104), IL6(3569)rat ... Ar(24208), Esr1(24890), Esr2(25149) |
| Storage Condition | desiccatedprotect from light |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (Z)-4-Hydroxytamoxifen used for?
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(Z)-4-Hydroxytamoxifen is primarily used in research settings for studying estrogen receptor modulation, endocrine functions, and potential antineoplastic effects in cancer research.
What is the CAS number and molecular formula for (Z)-4-Hydroxytamoxifen?
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The CAS number is 68047-06-3 and the molecular formula is C26H29NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (Z)-4-Hydroxytamoxifen at a PREMIUM quality level with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should (Z)-4-Hydroxytamoxifen be handled?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Use a full-face particle respirator (N100 US) or appropriate filter cartridges (P1 or P3 EN143). Avoid inhalation, ingestion, and skin contact due to potential health hazards (H302, H312, H332, H361).
How is (Z)-4-Hydroxytamoxifen typically shipped?
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As a global supplier and exporter, Tech Serve Solutions ensures appropriate packaging and shipping methods for research chemicals, maintaining necessary storage conditions during transit.
How can I request a quote or sample for (Z)-4-Hydroxytamoxifen?
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Please contact our sales team through the website to request a quotation or a sample of (Z)-4-Hydroxytamoxifen.
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