(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (CAS: 138472-01-2) is a chemical compound with the molecular formula C8H13N3O4 and a molecular weight of 215.21 g/mol. It functions as a cell-permeable nitric oxide (NO) donor, spontaneously releasing NO in a controlled manner with a half-life of approximately 30 minutes in solution. This compound is valuable in biochemical research for studying NO signaling pathways and cellular responses to NO.
- IUPAC
- NOR-3
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Life Science, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
Nitric Oxide (NO) Donation
This compound acts as a cell-permeable nitric oxide donor. It releases NO spontaneously and in a rate-controlled manner, making it useful for in vitro studies investigating the physiological and pathological roles of NO.
Cellular Signaling Research
As a source of NO, it is employed in research focused on cell signaling pathways, particularly those involving NO as a second messenger. Its controlled release mechanism aids in understanding dose-dependent cellular responses.
Biochemical Assays
Utilized in biochemical assays to probe enzymes and pathways affected by nitric oxide. The defined half-life allows for more precise experimental design when studying NO-mediated processes in biological systems.
| Molecular weight | 215.21 |
|---|---|
| Empirical formula | C8H13N3O4 |
| Assay | ≥98% |
| Storage temperature | −20°C |
| Application | Cell-permeable NO donor; releases nitric oxide spontaneously in a rate-controlled manner. Half-life in solution = 30 min. |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide used for?
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(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide is used as a cell-permeable nitric oxide (NO) donor that releases NO spontaneously in a rate-controlled manner, with a half-life of approximately 30 minutes in solution. It is valuable in biochemical research for studying NO signaling pathways and cellular responses.
What are the CAS number and formula for this compound?
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The CAS number is 138472-01-2 and the molecular formula is C8H13N3O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of ≥98%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should (±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide be handled safely?
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This compound is classified with GHS06 and the signal word 'Danger', carrying hazard statement H301 (Toxic if swallowed). Recommended personal protective equipment includes eyeshields, face shields, gloves, and P2 respirator cartridges. Handle with extreme care, avoiding ingestion and ensuring adequate ventilation. Refer to the Safety Data Sheet for full handling instructions.
How is this chemical packed, shipped, and exported?
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This chemical is stored at -20°C. TSS is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, adhering to international shipping regulations for hazardous materials.
How can I request a quote or sample?
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Please contact Tech Serve Solutions directly through our website or sales department to request a quote or a sample of (±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide.
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