(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (CAS: 162626-99-5; Molar Mass: 306.32 g/mol) is a bioactive small molecule recognised for its role as a nitric oxide (NO) donor. It releases NO spontaneously in a rate-controlled manner, with a half-life of approximately 60 minutes in solution. This compound is valuable in biochemical research and cell biology studies, particularly concerning cell signaling and NO metabolism.
- IUPAC
- NOR-4
![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Life Science, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
Nitric Oxide Research
This compound acts as a controlled nitric oxide donor, facilitating research into the physiological and pathological roles of NO in biological systems. Its predictable release kinetics are useful for studying cellular responses to NO.
Cell Signaling Studies
As a NO donor, it can be employed to investigate signaling pathways modulated by nitric oxide, including those related to cell stress and neuroscience. The compound helps researchers explore the complex mechanisms of cellular communication.
Enzyme and Substrate Research
This chemical is classified under enzyme substrates and is relevant for studies involving enzymes and their inhibitors, particularly in the context of nitric oxide metabolism and related cellular processes.
| Molecular weight | 306.32 |
|---|---|
| Empirical formula | C14H18N4O4 |
| Assay | ≥97% |
| Storage temperature | −20°C |
| Application | NO donor; releases nitric oxide spontaneously in a rate-controlled manner. Half-life in solution = 60 min. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide used for?
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This compound is primarily used as a nitric oxide (NO) donor in research. It releases NO spontaneously in a rate-controlled manner and is valuable for studying cell signaling, NO metabolism, and cell stress in areas like cell biology and neuroscience.
What are the CAS number and formula for this compound?
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The CAS number is 162626-99-5 and the empirical formula is C14H18N4O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of ≥97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should (±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide be handled?
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Based on GHS classification, this compound is a warning substance. It may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation.
Is this compound controlled or scheduled?
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The provided data does not indicate that this compound is a controlled substance.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging for safe transit and compliance with international shipping regulations. Specific packaging details are available upon request.
How can I request a sample or a quote?
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To request a sample or obtain a quote for (±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide, please contact our sales department through the website or provide your details for a prompt response.
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