(+)-(S)-N,N-Dimethyl-1-[(R)-1′,2-bis(diphenylphosphino)ferrocenyl]ethylamine
(+)-(S)-N,N-Dimethyl-1-[(R)-1′,2-bis(diphenylphosphino)ferrocenyl]ethylamine (CAS 55650-59-4) is a chiral ferrocenyl ligand with the molecular formula C38H37FeNP2 and a molecular weight of 625.50. This compound serves as a crucial ligand in asymmetric synthesis, particularly noted for its application in the asymmetric hydrogenation of specific types of unsaturated carboxylic acids. Its specific stereochemistry makes it valuable for enantioselective catalysis.
- Synonyms
- 55650-59-4
![(+)-(S)-N,N-Dimethyl-1-[(R)-1′,2-bis(diphenylphosphino)ferrocenyl]ethylamine (C38H37FeNP2) — chemical structure, CAS 55650-59-4; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F55650-59-4.png&w=3840&q=75)
Asymmetric Hydrogenation Ligand
This ferrocenyl ligand is employed in asymmetric hydrogenation reactions. It facilitates the enantioselective reduction of prochiral olefins, such as (Z)-α-amido-cinnamic acids, leading to chiral products with high enantiomeric excess.
Chiral Catalyst Component
It functions as a key component in the construction of chiral transition metal catalysts. The unique structure of the ligand can induce asymmetry during catalytic transformations, crucial for producing enantiomerically pure compounds.
Organic Synthesis Reagent
Utilized in advanced organic synthesis for creating stereodefined molecules. Its application is particularly relevant in the pharmaceutical and fine chemical industries where enantiopurity is paramount.
| Molecular weight | 625.50 |
|---|---|
| Empirical formula | C38H37FeNP2 |
| Assay | 95% |
| Optical activity | [α]20/D +350°, c = 0.5 in chloroform |
| Application | Ligand used in the asymmetric hydrogenation of (Z)-α-amido-cinnamic acids |
| Melting point | 138-142 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (+)-(S)-N,N-Dimethyl-1-[(R)-1′,2-bis(diphenylphosphino)ferrocenyl]ethylamine used for?
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(+)-(S)-N,N-Dimethyl-1-[(R)-1′,2-bis(diphenylphosphino)ferrocenyl]ethylamine (CAS 55650-59-4) is primarily used as a chiral ligand in asymmetric hydrogenation reactions, especially for the reduction of (Z)-α-amido-cinnamic acids.
What is the CAS number and molecular formula for this compound?
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The CAS number is 55650-59-4, and the empirical formula is C38H37FeNP2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with a minimum purity of 95%. This is a research-grade chemical; we do not represent it as USP, BP, or EP grade.
What are the safety and handling precautions for this chemical?
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This compound is harmful if swallowed, in contact with skin, or if inhaled, and causes skin and serious eye irritation, and may cause respiratory irritation. Always use a dust mask (type N95 US), wear eyeshields and gloves, and ensure good ventilation. Handle in accordance with the safety data sheet.
How is this chemical packed and shipped?
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Products are carefully packed and shipped by our experienced logistics team to meet international export regulations. We ensure secure transit for global delivery.
How can I request a sample or quote for this product?
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To request a sample or a quotation, please contact our sales department via the website or by email, providing the product name and CAS number.
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