(+)-1,2-Bis[(2R,5R)-2,5-diethylphospholano]ethane
(+)-1,2-Bis[(2R,5R)-2,5-diethylphospholano]ethane (CAS: 136705-62-9) is a chiral diphosphine ligand with the formula C18H36P2 and a molecular weight of 314.43 g/mol. This highly effective ligand is widely recognised for its role in asymmetric synthesis, particularly in catalytic applications. It belongs to the privileged class of DuPhos and BPE ligands, known for facilitating high enantioselectivity in various chemical transformations.
- IUPAC
- (R,R)-Et-BPE
- Synonyms
- 5R)-2, 136705-62-9, (R,R)-Et-BPE, 1,2-Bis(2,5-diethylphospholano)ethane, (2R,5R)-1,2-Bis(2,5-diethylphospholano)ethane
![(+)-1,2-Bis[(2R,5R)-2,5-diethylphospholano]ethane (5R)-2) — chemical structure, CAS 136705-62-9; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F136705-62-9.png&w=3840&q=75)
Asymmetric Catalysis
Serves as a crucial chiral ligand in metal-catalysed asymmetric reactions, enabling the synthesis of enantiomerically enriched compounds. Its effectiveness is well-documented in processes like asymmetric hydrogenation and carbon-carbon bond formation.
Chiral Synthesis
Integral to the development of sophisticated chiral molecules, including pharmaceutical intermediates and fine chemicals. The (2R,5R) configuration of the phospholane rings is key to its stereochemical control.
Ligand in Homogeneous Catalysis
Acts as a bidentate ligand, coordinating with transition metals to form active catalytic species. Its unique bite angle and electronic properties contribute to high catalytic efficiency and selectivity.
| Molecular weight | 314.43 |
|---|---|
| Empirical formula | C18H36P2 |
| Boiling point | 104-106 °C/0.05 mmHg |
| Density | 0.939 g/mL at 25 °C |
| Refractive index | n20/D 1.5249 |
| Application | DuPhos and BPE Ligands: Highly Efficient Privileged Ligands |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (+)-1,2-Bis[(2R,5R)-2,5-diethylphospholano]ethane used for?
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This compound is primarily used as a chiral ligand in asymmetric catalysis for the synthesis of enantiomerically enriched compounds, particularly in areas like pharmaceutical intermediate production and fine chemical synthesis.
What is the CAS number and formula for this chemical?
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The CAS number is 136705-62-9 and the empirical formula is C18H36P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. The specific grade and purity available may vary; please refer to the product specifications or contact us for detailed information. This product is not represented as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated in the specifications.
What are the safety and handling precautions for this chemical?
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According to the WGK (Germany), this chemical has a hazard classification of 3, indicating it is a substance that should not be released into water. Handle with appropriate personal protective equipment in a well-ventilated area. Avoid contact with skin, eyes, and clothing, and prevent inhalation.
How is this chemical packed and shipped?
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Tech Serve Solutions exports chemicals globally, adhering to all necessary regulations for safe and compliant transportation. Packaging is selected to ensure product integrity and safety during transit.
How can I request a quote or sample?
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To request a quote or a sample, please visit the product page on our website and use the 'Request a Quote' or 'Request a Sample' functionality, or contact our sales department directly.
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