(+)-(8,8-Dichlorocamphorylsulfonyl)oxaziridine

CAS 127184-05-8C10H13Cl2NO3SChemical Synthesis

(+)-(8,8-Dichlorocamphorylsulfonyl)oxaziridine (CAS: 127184-05-8) is a chiral reagent with a molecular weight of 298.19 g/mol. It is primarily utilised in asymmetric synthesis for the enantioselective introduction of functional groups, particularly in the formation of chiral centres through oxidation reactions. Its specific stereochemical properties make it a valuable tool for chemists requiring high levels of enantiomeric purity in their synthetic targets.

IUPAC: (+)-3,3-Dichloro-2,N-epoxy-exo-10,2-bornanesultam
Synonyms: C10H13Cl2NO3S

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(+)-(8,8-Dichlorocamphorylsulfonyl)oxaziridine (C10H13Cl2NO3S) — chemical structure, CAS 127184-05-8; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral CatalystsLigandsand ReagentsHydroxylation

01 /Applications

Asymmetric Synthesis

This reagent is extensively employed in asymmetric synthesis to control stereochemistry during chemical transformations. It enables the formation of chiral molecules with high enantiomeric excess, crucial for pharmaceutical and fine chemical development.

Chiral Oxidation Reagent

It serves as an effective chiral oxidizing agent, particularly for the enantioselective hydroxylation of enolates and related nucleophiles. This capability is vital for constructing complex chiral building blocks.

Pharmaceutical Intermediate Synthesis

Its application extends to the synthesis of complex pharmaceutical intermediates where precise stereochemical control is paramount. It aids in the efficient creation of enantiomerically pure drug precursors.

02 /Properties

Molecular weight	298.19
Empirical formula	C10H13Cl2NO3S
Assay	≥97.0% (T)
Optical activity	[α]20/D +89±3°, c = 0.5% in chloroform
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

127184-05-8

MDL number

MFCD00243015

Beilstein registry

3653352

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (+)-(8,8-Dichlorocamphorylsulfonyl)oxaziridine used for?

(+)-(8,8-Dichlorocamphorylsulfonyl)oxaziridine is used in asymmetric synthesis and as a chiral oxidation reagent, particularly for enantioselective hydroxylation.

What is the CAS number and molecular formula?

The CAS number is 127184-05-8 and the empirical formula is C10H13Cl2NO3S.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (+)-(8,8-Dichlorocamphorylsulfonyl)oxaziridine with an assay of 97.0% (T). TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.

How should (+)-(8,8-Dichlorocamphorylsulfonyl)oxaziridine be handled?

Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation, and use a type N95 (US) or type P1 (EN143) respirator filter if necessary, as indicated by the WGK Germany rating of 3.

How is this chemical shipped and exported?

Tech Serve Solutions, as a specialist global supplier and exporter, ships and exports chemicals worldwide. Specific shipping and handling comply with international regulations.