(+)-1,2-Bis[(2S,5S)-2,5-diethylphospholano]benzene
(+)-1,2-Bis[(2S,5S)-2,5-diethylphospholano]benzene (CAS: 136779-28-7), with the empirical formula C22H36P2 and a molecular weight of 362.47 g/mol, is a sophisticated chiral diphosphine ligand. It is primarily employed in asymmetric synthesis, where its unique structure facilitates high enantioselectivity in catalytic reactions. This compound is a key component in advanced chemical synthesis, particularly in the development of chiral catalysts and reagents.
- IUPAC
- (2S,2′S,5S,5′S)-2,2′,5,5′-Tetraethyl-1,1′-(o-phenylene)diphospholane,(S,S)-Ethyl-DUPHOS
- Synonyms
- 5-diethylphospholano]benzene(S,S)-Ethyl-DUPHOS(2S,2′S,5S,5′S)-2,2′,5,5′-Tetraethyl-1,1′-(o-phenylene)diphospholane
![(+)-1,2-Bis[(2S,5S)-2,5-diethylphospholano]benzene (5S)-2) — chemical structure, CAS 136779-28-7; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F136779-28-7.png&w=3840&q=75)
Asymmetric Catalysis
This ligand is extensively used in transition metal catalysis for enantioselective transformations. It enables the synthesis of chiral molecules with high optical purity, crucial for pharmaceutical and fine chemical industries.
Chiral Ligand Development
As a member of the DuPhos/BPE family, it represents a class of privileged ligands known for their robustness and efficacy. Its structure is integral to the design of new catalytic systems for challenging asymmetric reactions.
Chemical Synthesis
It serves as a valuable reagent in complex organic synthesis, contributing to stereocontrolled formation of carbon-carbon and carbon-heteroatom bonds.
| Molecular weight | 362.47 |
|---|---|
| Empirical formula | C22H36P2 |
| Density | 1.010 g/mL at 25 °C |
| Refractive index | n20/D 1.581 |
| Application | DuPhos and BPE Ligands: Highly Efficient Privileged Ligands |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (+)-1,2-Bis[(2S,5S)-2,5-diethylphospholano]benzene used for?
+
(+)-1,2-Bis[(2S,5S)-2,5-diethylphospholano]benzene is primarily used as a chiral ligand in asymmetric catalysis and for general chemical synthesis, especially in the development of chiral catalysts and reagents.
What are the CAS number and formula for (+)-1,2-Bis[(2S,5S)-2,5-diethylphospholano]benzene?
+
The CAS number is 136779-28-7 and the empirical formula is C22H36P2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this chemical with a typical purity suitable for research and synthesis applications. The specific assay will be detailed on the Certificate of Analysis provided with your order. We do not represent this product as meeting USP, BP, EP, or other pharmacopoeial standards.
How should (+)-1,2-Bis[(2S,5S)-2,5-diethylphospholano]benzene be handled safely?
+
This compound is classified as a Warning, with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Always handle with appropriate personal protective equipment, including eyeshields and gloves, and ensure adequate ventilation or use a suitable respirator. Avoid breathing dust/fume/gas/mist/vapours/spray.
Is this chemical suitable for export?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and reagents, and we can export (+)-1,2-Bis[(2S,5S)-2,5-diethylphospholano]benzene to international customers.
How can I request a sample or quote?
+
To request a sample or a quotation for (+)-1,2-Bis[(2S,5S)-2,5-diethylphospholano]benzene, please contact our sales team via the website or by calling our main office. Please specify the quantity required.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis