(+)-1,4-Di-O-benzyl-D-threitol
(+)-1,4-Di-O-benzyl-D-threitol (CAS: 91604-41-0), a chiral carbohydrate derivative with the molecular formula C18H22O4, is a valuable building block in organic synthesis. Its structure, featuring protected diol functionalities, makes it ideal for stereoselective reactions and the construction of complex molecules. Commonly employed in carbohydrate chemistry and chemical synthesis, this compound serves as a versatile intermediate.
- IUPAC
- (2R,3R)-(+)-1,4-Bis(benzyloxy)-2,3-butanediol
- Synonyms
- (2R,3R)-(+)-1,4-Bis(benzyloxy)-2,3-butanediol

Chiral Building Block in Organic Synthesis
Utilised as a stereodefined starting material for the synthesis of complex chiral molecules, including natural products and pharmaceuticals. The benzyl protecting groups allow for selective manipulation of the molecule's core structure.
Intermediate in Carbohydrate Chemistry
Serves as a key intermediate in the synthesis and modification of carbohydrate structures. Its protected diol functionality facilitates regioselective reactions and the creation of novel glycosides.
Precursor for Ligand Synthesis
Can be employed in the development of chiral ligands for asymmetric catalysis. The inherent chirality and functional groups are amenable to modification for specific catalytic applications.
| Molecular weight | 302.36 |
|---|---|
| Empirical formula | C18H22O4 |
| Assay | ≥97.0% (TLC) |
| Grade | purum |
| Optical activity | [α]20/D +6.0±0.5°, c = 5% in chloroform |
| Melting point | 55-58 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (+)-1,4-Di-O-benzyl-D-threitol used for?
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(+)-1,4-Di-O-benzyl-D-threitol is used as a chiral building block in organic synthesis, particularly in carbohydrate chemistry and for the preparation of complex molecules and ligands.
What is the CAS number and molecular formula for (+)-1,4-Di-O-benzyl-D-threitol?
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The CAS number is 91604-41-0 and the empirical formula is C18H22O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (+)-1,4-Di-O-benzyl-D-threitol with a purity of ≥97.0% (TLC), graded as purum. We do not represent this product as USP, BP, or EP grade.
How should (+)-1,4-Di-O-benzyl-D-threitol be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. This compound is classified with WGK 2 in Germany, indicating it is hazardous to water.
How is (+)-1,4-Di-O-benzyl-D-threitol packed, shipped, and exported?
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As a global supplier, Tech Serve Solutions exports (+)-1,4-Di-O-benzyl-D-threitol worldwide, adhering to all relevant shipping and customs regulations for chemical products.
How can I request a sample or quote for (+)-1,4-Di-O-benzyl-D-threitol?
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You can request a sample or a quotation by contacting our sales team through the provided channels on the Tech Serve Solutions website.
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