(+)-2,2′-Isopropylidenebis[(4R)-4-benzyl-2-oxazoline]
(+)-2,2′-Isopropylidenebis[(4R)-4-benzyl-2-oxazoline] (CAS: 141362-77-8), a chiral ligand with a molecular weight of 362.46 g/mol, is a valuable reagent in asymmetric synthesis. This compound, also known as BOX, is instrumental in creating stereoselective reactions, particularly in the synthesis of complex organic molecules. Its specific chiral structure allows for precise control over the stereochemical outcome of transformations, making it a key component in advanced chemical research and development.
- IUPAC
- (R,R)-(+)-2,2′-Isopropylidenebis(4-benzyl-2-oxazoline),[R(R*,R*)]-(+)-2,2′-Isopropylidenebis(4-benzyl-2-oxazoline)
- Synonyms
- (R,R)-(+)-2,2′-Isopropylidenebis(4-benzyl-2-oxazoline)[R(R*,R*)]-(+)-2,2′-Isopropylidenebis(4-benzyl-2-oxazoline)
![(+)-2,2′-Isopropylidenebis[(4R)-4-benzyl-2-oxazoline] (C23H26N2O2) — chemical structure, CAS 141362-77-8; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F141362-77-8.png&w=3840&q=75)
Asymmetric Catalysis
This oxazoline ligand serves as a crucial component in metal-catalyzed asymmetric reactions. It effectively directs the stereochemical course of reactions, leading to the enantioselective formation of chiral products.
Chiral Synthesis
It is widely employed in the synthesis of enantiomerically enriched compounds, playing a significant role in the development of pharmaceuticals and fine chemicals where specific stereoisomers are required.
Ligand in Organometallic Chemistry
As a bidentate ligand, it forms stable complexes with various transition metals, modulating their catalytic activity and selectivity in diverse organic transformations.
| Molecular weight | 362.46 |
|---|---|
| Empirical formula | C23H26N2O2 |
| Assay | 98% |
| Optical activity | [α]22/D +65°, c = 1 in ethanol |
| Storage temperature | 2-8°C |
| Melting point | 54-60 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (+)-2,2′-Isopropylidenebis[(4R)-4-benzyl-2-oxazoline] used for?
+
(+)-2,2′-Isopropylidenebis[(4R)-4-benzyl-2-oxazoline] is primarily used as a chiral ligand in asymmetric synthesis and catalysis to achieve stereoselective transformations.
What are the CAS number and formula for this compound?
+
The CAS number is 141362-77-8, and its empirical formula is C23H26N2O2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this chemical with an assay of 98%. We do not represent this product as meeting USP, BP, EP, or any other pharmacopoeia standards unless explicitly stated in the specifications.
How should this chemical be handled safely?
+
This compound is a Warning irritant (H315, H319, H335). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, in a well-ventilated area. Avoid breathing dust and ensure proper skin and eye protection.
How is this product shipped and exported?
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This product is shipped and exported by Tech Serve Solutions, adhering to all relevant international shipping regulations for chemical compounds. It is recommended to store the product at 2-8°C.
How can I request a sample or quote?
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Please contact our sales team directly through our website or via email to request a sample or a detailed quote for (+)-2,2′-Isopropylidenebis[(4R)-4-benzyl-2-oxazoline].
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