(+)-2,2′-Isopropylidenebis[(4R)-4-phenyl-2-oxazoline]
(+)-2,2′-Isopropylidenebis[(4R)-4-phenyl-2-oxazoline] (CAS: 150529-93-4), with a molecular formula of C21H22N2O2 and a molecular weight of 334.41 g/mol, is a C2 symmetric chiral ligand. Its nitrogen atoms readily form bidentate coordination complexes with various metals, making it a valuable reagent in asymmetric synthesis and enantioselective catalysis. The compound is supplied at a minimum assay of 97% and requires storage at -20°C.
- IUPAC
- (R,R)-2,2′-Bis(4-phenyl-2-oxazolin-2-yl)propane,(R,R)-2,2′-Isopropylidenebis(4-phenyl-2-oxazoline)
- Synonyms
- C21H22N2O2(R,R)-2,2′-Bis(4-phenyl-2-oxazolin-2-yl)propane(R,R)-2,2′-Isopropylidenebis(4-phenyl-2-oxazoline)
![(+)-2,2′-Isopropylidenebis[(4R)-4-phenyl-2-oxazoline] (C21H22N2O2) — chemical structure, CAS 150529-93-4; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F150529-93-4.png&w=3840&q=75)
Asymmetric Catalysis
This C2 symmetric ligand is highly effective in enantioselective catalysis. It forms stable bidentate coordination complexes with transition metals, facilitating stereoselective transformations.
Chiral Ligand Synthesis
Its structure makes it an ideal building block or ligand in the synthesis of chiral catalysts. The phenyl and oxazoline groups contribute to its effectiveness in directing stereochemistry.
Organic Synthesis Reagent
As a privileged ligand, it is employed in various organic synthesis reactions requiring high enantioselectivity. Its well-defined coordination chemistry enables precise control over reaction outcomes.
| Molecular weight | 334.41 |
|---|---|
| Empirical formula | C21H22N2O2 |
| Assay | 97% |
| Optical activity | [α]20/D +160°, c = 1 in ethanol |
| Storage temperature | −20°C |
| Application | C2 symmetric ligand for enantioselective catalysis. Easily forms bidentate coordination complexes due to the strong affinity of the oxazoline nitrogen for various metals.1,2,3 |
| Melting point | 56-58 °C(lit.) |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25 |
| Safety statements (S) | 26-36-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (+)-2,2′-Isopropylidenebis[(4R)-4-phenyl-2-oxazoline] used for?
+
This compound is primarily used as a C2 symmetric ligand in enantioselective catalysis. It readily forms bidentate coordination complexes with various metals, finding applications in asymmetric synthesis and chiral catalyst development.
What are the CAS number and formula for this chemical?
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The CAS number is 150529-93-4 and the empirical formula is C21H22N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with a minimum assay of 97%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should (+)-2,2′-Isopropylidenebis[(4R)-4-phenyl-2-oxazoline] be handled?
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This compound is classified as toxic if swallowed, in contact with skin, or if inhaled (H301 + H311 + H331). Handling requires strict adherence to safety protocols, including the use of eyeshields, faceshields, gloves, and P2 respirator cartridges. Work in a well-ventilated area or fume hood. In case of exposure, follow specific first aid measures as indicated in the Safety Data Sheet.
How is this chemical shipped and exported?
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This product is shipped and exported according to international regulations for hazardous materials, identified as UN 2811, Class 6.1, Packing Group III. TSS ensures compliance with all relevant shipping and export requirements.
How can I request a sample or quote?
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To request a sample or a quotation for (+)-2,2′-Isopropylidenebis[(4R)-4-phenyl-2-oxazoline], please contact our sales team via the website or by telephone, specifying the CAS number 150529-93-4 and the quantity required.
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