1-Naphthaleneacetic anhydride
1-Naphthaleneacetic anhydride (CAS: 5415-58-7) is a chemical compound with the linear formula (C<sub>10</sub>H<sub>7</sub>CH<sub>2</sub>CO)<sub>2</sub>O and a molecular weight of 354.40 g/mol. This carboxylic acid anhydride is employed in chemical synthesis and as a building block. Its fluorescence properties, with excitation at 216 nm and emission at 360 nm (for polyamin adducts), make it suitable for applications in fluorescent labelling and detection.
- IUPAC
- 1-Naphthylacetic anhydride
- Synonyms
- 1-Naphthylacetic anhydride

Chemical Synthesis
1-Naphthaleneacetic anhydride serves as a valuable reagent in organic synthesis. Its anhydride functionality allows for acylation reactions, facilitating the introduction of the 1-naphthaleneacetyl group into various molecules.
Fluorescent Labeling
With specific fluorescence excitation and emission wavelengths, this compound is utilised in the development of fluorescent probes and labels. These can be applied in biochemical research and analytical detection methods.
Building Block
As a chemical building block, 1-Naphthaleneacetic anhydride can be incorporated into more complex molecular structures. Its distinct naphthalene moiety offers unique properties for material science and pharmaceutical intermediate development.
| Molecular weight | 354.40 |
|---|---|
| Linear formula | (C10H7CH2CO)2O |
| Assay | 96% |
| Grade | for fluorescencepurum |
| Storage temperature | 2-8°C |
| Melting point | 116-119 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 216 nm; λem 360 nm (polyamin adduct) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Naphthaleneacetic anhydride used for?
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1-Naphthaleneacetic anhydride is used in chemical synthesis as a building block and for applications involving fluorescent labeling and detection due to its specific optical properties.
What are the CAS number and formula for 1-Naphthaleneacetic anhydride?
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The CAS number for 1-Naphthaleneacetic anhydride is 5415-58-7, and its linear formula is (C<sub>10</sub>H<sub>7</sub>CH<sub>2</sub>CO)<sub>2</sub>O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Naphthaleneacetic anhydride in purum grade with an assay of 96%. This product is intended for laboratory and research purposes and is not supplied as USP, BP, or EP grade.
How should 1-Naphthaleneacetic anhydride be handled safely?
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1-Naphthaleneacetic anhydride is classified as dangerous (GHS05, Danger) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection (e.g., P3 filter), is essential during handling. Refer to the Safety Data Sheet for comprehensive safety information.
How is 1-Naphthaleneacetic anhydride packed, shipped, and exported?
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1-Naphthaleneacetic anhydride is shipped as UN 3261, Hazard Class 8, Packing Group II, conforming to international transport regulations. Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals.
How can I request a quote or sample for 1-Naphthaleneacetic anhydride?
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To request a quote or a sample of 1-Naphthaleneacetic anhydride, please contact our sales department through the website or by phone, providing your specific requirements.
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