(+)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane
(+)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane (CAS 37002-48-5) is a chiral diphosphine ligand with the empirical formula C31H32O2P2 and a molecular weight of 498.53 g/mol. This compound is primarily utilised in asymmetric synthesis for the in situ preparation of chiral hydrogenation catalysts, enabling enantioselective transformations in organic chemistry. It is supplied by Tech Serve Solutions with a minimum assay of 98%.
- IUPAC
- (+)-DIOP,(+)-1,4-Bis(diphenylphosphino)-1,4-dideoxy-2,3-O-isopropylidene-D-threitol,(4S,5S)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane,(4S-trans)-[(2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene)]bis(diphenylphosphine),(S,S)-DIOP
- Synonyms
- (+)-DIOPDIOP4-bis(diphenylphosphino)butane,(S,S)-DIOP,(4S-trans)-[(2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene)]bis(diphenylphosphine),(4S,5S)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane
Chiral Hydrogenation Catalysis
This diphosphine ligand is used to prepare chiral hydrogenation catalysts. These catalysts are crucial for enantioselective reduction reactions, enabling the synthesis of chiral molecules with high stereochemical control.
Asymmetric Synthesis
As a key component in asymmetric synthesis, it facilitates the creation of enantiomerically enriched products. Its chiral structure directs the stereochemical outcome of catalytic reactions.
Ligand for Transition Metal Complexes
It functions as a privileged ligand, coordinating with transition metals to form active catalytic species. These complexes are vital in various catalytic processes requiring stereoselectivity.
| Molecular weight | 498.53 |
|---|---|
| Empirical formula | C31H32O2P2 |
| Assay | 98% |
| Optical activity | [α]19/D +26°, c = 2.3 in chloroform |
| Storage temperature | 2-8°C |
| Application | For the in situ preparation of chiral hydrogenation catalysts. |
| Melting point | 86-88 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (+)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane used for?
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This compound is used for the in situ preparation of chiral hydrogenation catalysts, serving as a privileged ligand in asymmetric synthesis for enantioselective transformations.
What is the CAS number and empirical formula?
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The CAS number is 37002-48-5 and the empirical formula is C31H32O2P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with a minimum assay of 98%. This product is not represented as USP, BP, or EP grade.
How should (+)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane be handled and stored?
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Handle with appropriate personal protective equipment including a dust mask type N95 (US), eyeshields, and gloves. It is irritating to the eyes, respiratory system, and skin. Store at 2-8°C.
Is this chemical a controlled substance?
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Based on the provided data, there is no indication that this chemical is a controlled substance.
How can I request a sample or quote for this product?
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Please contact Tech Serve Solutions directly via our website or sales department to request a sample or a formal quotation for this product.
How is this chemical packed and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures products are packed and exported in compliance with relevant regulations for safe international shipping.
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