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(+)-3-(Trifluoroacetyl)camphor

CAS 51800-98-7C12H15F3O2Chemical Synthesis

(+)-3-(Trifluoroacetyl)camphor (CAS 51800-98-7; C12H15F3O2; MW 248.24) is a chiral ketone widely employed in asymmetric synthesis. Its trifluoroacetyl group enhances its reactivity and utility as a chiral auxiliary or building block in stereoselective transformations. Available from Tech Serve Solutions with an assay of 98%, this compound is a valuable reagent for researchers and chemists engaged in the synthesis of complex organic molecules, particularly in the pharmaceutical and fine chemical industries.

IUPAC
3-(Trifluoroacetyl)-D-camphor
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(+)-3-(Trifluoroacetyl)camphor (C12H15F3O2) — chemical structure, CAS 51800-98-7; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral Building BlocksKetonesOrganic Building Blocks
01 /Applications

Chiral Auxiliary in Asymmetric Synthesis

(+)-3-(Trifluoroacetyl)camphor serves as a chiral auxiliary to induce stereoselectivity in various organic reactions. It can be temporarily incorporated into a molecule to direct the stereochemical outcome of a subsequent transformation before being cleaved.

Chiral Building Block

This compound acts as a chiral building block for the construction of enantiomerically enriched molecules. Its inherent chirality and functional groups allow for its integration into complex target structures.

Reagent in Stereoselective Reactions

It is utilised as a reagent in stereoselective reactions, enabling the synthesis of specific enantiomers of desired products. The trifluoroacetyl moiety influences reaction pathways and stereochemical control.

02 /Properties
Molecular weight248.24
Empirical formulaC12H15F3O2
Assay98%
Boiling point100-101 °C/16 mmHg(lit.)
Density1.172 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.451(lit.)
Optical activity[α]19/D +148°, c = 2.3 in methylene chloride
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentEyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point82 °C / 179.6 °F
Transport (UN / ADR)NA 1993 / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
51800-98-7
MDL number
MFCD00003746
PubChem substance
24851361
Beilstein registry
6779716
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (+)-3-(Trifluoroacetyl)camphor used for?

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(+)-3-(Trifluoroacetyl)camphor is primarily used as a chiral auxiliary and building block in asymmetric synthesis and stereoselective reactions.

What are the CAS number and molecular formula?

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The CAS number for (+)-3-(Trifluoroacetyl)camphor is 51800-98-7, and its molecular formula is C12H15F3O2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (+)-3-(Trifluoroacetyl)camphor with an assay of 98%. This is a research-grade chemical and is not represented as USP, BP, or EP grade.

How should (+)-3-(Trifluoroacetyl)camphor be handled?

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Based on GHS classifications, this compound may cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment including eyeshields, gloves, and respiratory protection should be used when handling.

Is this chemical shipped internationally?

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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (+)-3-(Trifluoroacetyl)camphor.

How can I request a sample or quote?

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Please contact our sales team or use the product enquiry form on our website to request a sample or a quotation for (+)-3-(Trifluoroacetyl)camphor.

Need (+)-3-(Trifluoroacetyl)camphor in a specific grade or volume?