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4-Azidophenyl isothiocyanate

CAS 74261-65-7N3C6H4NCSChemical Synthesis

4-Azidophenyl isothiocyanate (CAS: 74261-65-7; Formula: N3C6H4NCS) is a reactive organic compound with a molecular weight of 176.20 g/mol. As an aromatic azide and isothiocyanate derivative, it serves as a valuable building block in chemical synthesis. Its unique bifunctional nature allows for diverse applications in organic chemistry, particularly in the development of novel molecules and materials. Stored under refrigeration, this compound is supplied by Tech Serve Solutions for research and development purposes.

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4-Azidophenyl isothiocyanate (N3C6H4NCS) — chemical structure, CAS 74261-65-7; Chemistry, fine chemical supplied by Tech Serve Solutions
Aromatic AzidesAzidesBuilding BlocksChemical SynthesisNitrogen Compounds
01 /Applications

Organic Synthesis Intermediate

4-Azidophenyl isothiocyanate functions as a versatile intermediate in the synthesis of complex organic molecules. Its azide and isothiocyanate groups offer distinct reaction pathways for molecular construction.

Bioconjugation Reagent

The azide functionality can be utilised in click chemistry reactions for bioconjugation, enabling the labelling or modification of biomolecules. The isothiocyanate group can react with amines, further expanding its utility.

Material Science Research

This compound can be incorporated into polymers or functionalised materials. Its reactive groups allow for the development of tailored materials with specific chemical or physical properties.

02 /Properties
Molecular weight176.20
Linear formulaN3C6H4NCS
Assay≥97.0% (CHN)
Storage temperature2-8°C
Melting point65-68 °C(lit.)66-68 °C
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
GHS hazard pictogram: Health hazard (GHS08)
Health hazard
Danger

Hazard statements

  • H228Flammable solid
  • H302Harmful if swallowed
  • H312Harmful in contact with skin
  • H315Causes skin irritation
  • H317May cause an allergic skin reaction
  • H319Causes serious eye irritation
  • H332Harmful if inhaled
  • H334May cause allergy or asthma symptoms if inhaled
  • H335May cause respiratory irritation

Precautionary statements

  • P210Keep away from heat, sparks and open flames. No smoking
  • P261Avoid breathing dust, fume, gas or vapours
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P342
Protective equipmentEyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Transport (UN / ADR)UN 1325 4.1 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)F,Xn
Risk statements (R)11-20/21/22-36/37/38-42
Safety statements (S)22-26-36/37/39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
74261-65-7
MDL number
MFCD00042980
PubChem substance
24847223
Beilstein registry
6391971
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-Azidophenyl isothiocyanate used for?

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4-Azidophenyl isothiocyanate is primarily used as a building block in organic synthesis, for bioconjugation reactions via click chemistry, and in material science research.

What is the CAS number and formula for 4-Azidophenyl isothiocyanate?

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The CAS number is 74261-65-7, and the chemical formula is N3C6H4NCS.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 4-Azidophenyl isothiocyanate with an assay of <div class="flex flex-col items-center justify-center gap-y-3 mt-6"> <h2 class="text-xl font-bold">Faqs</h2> <div class="flex flex-col"> <p class="font-bold">Is 4-Azidophenyl isothiocyanate safe to handle?</p> <p class="ml-4">4-Azidophenyl isothiocyanate is a Danger substance. It is flammable and harmful if swallowed, inhaled, or in contact with skin. It can cause skin and eye irritation, and respiratory irritation. Appropriate personal protective equipment, including eyeshields, gloves, and a respirator, must be used. Refer to the safety data sheet for detailed handling instructions.</p> </div> <div class="flex flex-col"> <p class="font-bold">How is 4-Azidophenyl isothiocyanate shipped and exported?</p> <p class="ml-4">As a UN 1325, 4.1 / PGII substance, 4-Azidophenyl isothiocyanate is subject to specific regulations for transportation. Tech Serve Solutions ensures compliance with all relevant shipping and export guidelines for hazardous materials.</p> </div> <div class="flex flex-col"> <p class="font-bold">How do I request a sample or quote for 4-Azidophenyl isothiocyanate?</p> <p class="ml-4">To request a sample or a quote for 4-Azidophenyl isothiocyanate, please contact our sales department through the website or by phone. Our team will be happy to assist you with your specific requirements.</p> </div> </div> </div>

What are the storage conditions for 4-Azidophenyl isothiocyanate?

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4-Azidophenyl isothiocyanate should be stored at 2-8°C to maintain its stability and quality.

What is the melting point of 4-Azidophenyl isothiocyanate?

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The melting point of 4-Azidophenyl isothiocyanate is typically between 65-68°C.

Need 4-Azidophenyl isothiocyanate in a specific grade or volume?