(4-Nitrobenzyl)triphenylphosphonium bromide
(4-Nitrobenzyl)triphenylphosphonium bromide (CAS: 2767-70-6) is a versatile Wittig reagent with the molecular formula O2NC6H4CH2P(C6H5)3Br and a molecular weight of 480.33 g/mol. It is a key intermediate in organic synthesis, facilitating C-C bond formation. This compound finds significant application in the creation of diverse organic molecules, including stilbene derivatives, distyrylfurans, pyrethroids, and pyridinylidene amines.
- IUPAC
- Bromo[(4-nitrophenyl)methyl]triphenylphosphorane,NSC 104840,NSC 617038
Synthesis of PPAR Agonists
Serves as a reactant in the synthesis of PPAR agonists, which are derived from LXR antagonists, contributing to advanced pharmaceutical research.
Stilbene Derivative Preparation
Utilised in the preparation of stilbene derivatives for applications in nerve agent detection and for creating fluorescent polymers.
Distyrylfuran Synthesis
A key reagent in the synthetic pathway for producing distyrylfurans, contributing to the field of materials science and organic electronics.
Pyrethroid Insecticides
Employed in the synthesis of pyrethroids, a class of compounds known for their potent insecticidal activity, important for agricultural applications.
Antimalarial Agents
A reactant in the synthesis of pyridinylidene amines, which exhibit antimalarial activity, offering potential in the development of new therapeutic agents.
| Molecular weight | 480.33 |
|---|---|
| Linear formula | O2NC6H4CH2P(C6H5)3Br |
| Assay | 97% |
| Application | Reactant for the synthesis of: • PPAR agonists derived from LXR antagonists1• Stilbene derivatives for use in detection of nerve agents2 and for attaching to polymers to elicit fluorescent behavior3• Distyrylfurans4• Pyrethoids with insecticidal activity5• Pyridinylidene amines with antimalarial activity6 |
| Melting point | 275 °C (dec.)(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (4-Nitrobenzyl)triphenylphosphonium bromide primarily used for?
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(4-Nitrobenzyl)triphenylphosphonium bromide is primarily used as a Wittig reagent for C-C bond formation in organic synthesis, facilitating the creation of various complex organic molecules like stilbene derivatives, distyrylfurans, pyrethroids, and pyridinylidene amines.
What are the CAS number and formula for (4-Nitrobenzyl)triphenylphosphonium bromide?
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The CAS number is 2767-70-6 and the linear formula is O2NC6H4CH2P(C6H5)3Br.
What grade and purity does Tech Serve Solutions supply for (4-Nitrobenzyl)triphenylphosphonium bromide?
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Tech Serve Solutions supplies (4-Nitrobenzyl)triphenylphosphonium bromide with an assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated in the product specifications.
How should (4-Nitrobenzyl)triphenylphosphonium bromide be handled safely?
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This compound is an irritant to the skin, eyes, and respiratory tract (H315, H319, H335). When handling, wear appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation.
Is (4-Nitrobenzyl)triphenylphosphonium bromide a controlled substance?
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The provided data does not indicate that (4-Nitrobenzyl)triphenylphosphonium bromide is a controlled substance.
How is (4-Nitrobenzyl)triphenylphosphonium bromide packed, shipped, and exported?
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As a specialist global supplier, Tech Serve Solutions ensures secure and compliant packing, shipping, and exporting of all chemicals, including (4-Nitrobenzyl)triphenylphosphonium bromide, according to international regulations.
How can I request a sample or quote for (4-Nitrobenzyl)triphenylphosphonium bromide?
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To request a sample or a quote for (4-Nitrobenzyl)triphenylphosphonium bromide, please contact our sales team through the website or direct inquiry channels.
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