(R)-(–)-2-(Trifluoromethyl)pyrrolidine
(R)-(–)-2-(Trifluoromethyl)pyrrolidine (CAS: 119618-29-0, C5H8F3N) is a chiral fluorinated heterocyclic compound with a molecular weight of 139.12 g/mol. This versatile building block finds significant application in asymmetric synthesis and chemical research. Its unique trifluoromethyl substituent and pyrrolidine ring structure make it valuable for introducing chirality and fluorine atoms into complex organic molecules, contributing to advancements in medicinal chemistry and materials science.
Asymmetric Synthesis
Serves as a chiral building block for the stereoselective synthesis of complex organic molecules, enabling the creation of enantiomerically pure compounds.
Pharmaceutical Intermediates
Used in the development and synthesis of novel pharmaceutical agents where specific stereochemistry and fluorine incorporation are critical for biological activity.
Chemical Research
Employed as a reagent in academic and industrial research for exploring new synthetic methodologies and developing novel fluorinated compounds.
Heterocyclic Chemistry
A valuable synthon for constructing functionalized heterocyclic systems, particularly pyrrolidine derivatives with fluorinated substituents.
| Molecular weight | 139.12 |
|---|---|
| Empirical formula | C5H8F3N |
| Assay | 97% |
| Boiling point | 110-111 °C |
| Storage temperature | 2-8°C |
| Melting point | 29-33 °C |
Hazard statements
- H228Flammable solid
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H400Very toxic to aquatic life
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 28 °C / 82.4 °F |
| Transport (UN / ADR) | UN 1325 4.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn,N |
| Risk statements (R) | 11-22-36/37/38-50 |
| Safety statements (S) | 16-26-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(–)-2-(Trifluoromethyl)pyrrolidine used for?
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(R)-(–)-2-(Trifluoromethyl)pyrrolidine is primarily used in asymmetric synthesis and as a chiral building block for creating complex organic molecules, particularly in pharmaceutical research and development.
What are the CAS number and formula for this compound?
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The CAS number is 119618-29-0, and the empirical formula is C5H8F3N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(–)-2-(Trifluoromethyl)pyrrolidine with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should (R)-(–)-2-(Trifluoromethyl)pyrrolidine be handled safely?
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This compound is flammable and harmful if swallowed, causing skin and eye irritation, and respiratory irritation. It is also toxic to aquatic life. Handle with appropriate personal protective equipment including eyeshields, gloves, and a suitable respirator. Ensure good ventilation and avoid release into the environment. Store at 2-8°C.
Is (R)-(–)-2-(Trifluoromethyl)pyrrolidine a controlled substance?
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The provided data does not indicate that (R)-(–)-2-(Trifluoromethyl)pyrrolidine is a controlled substance.
How is this chemical shipped and exported?
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As a supplier and exporter of fine chemicals, Tech Serve Solutions handles packaging and shipping in compliance with international regulations for hazardous materials, including UN 1325, Class 4.1, Packing Group III.
How can I request a quote or sample?
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To request a quote or sample of (R)-(–)-2-(Trifluoromethyl)pyrrolidine, please contact our sales team through the TSS website or by phone.
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