Propionyl-leupeptin hemisulfate salt
Propionyl-leupeptin hemisulfate salt (CAS: 24365-46-6) is a protease inhibitor with the molecular formula C21H40N6O4 · 1/2H2SO4. It functions by inhibiting serine proteases. This compound is primarily utilized in biochemical research, particularly in studies involving cell biology, cell signaling, and neuroscience. Its ability to block enzymatic activity makes it a valuable reagent for controlling protein degradation in experimental settings.
- IUPAC
- Propionyl-Leu-Leu-Arg-al

Protease Inhibition in Research
Propionyl-leupeptin hemisulfate salt serves as an effective inhibitor of serine proteases. This activity is crucial for preventing protein degradation during sample preparation and experimentation in various biological research fields.
Cell Biology Studies
In cell biology, this compound aids in maintaining cellular integrity by inhibiting endogenous proteases. It supports research into cellular processes where uncontrolled protein breakdown could confound results.
Neuroscience Research
This inhibitor is employed in neuroscience to study the roles of proteases in neural pathways and signaling. Its use helps elucidate complex molecular mechanisms within the nervous system.
Biochemical Assays
Propionyl-leupeptin hemisulfate salt can be included in biochemical assays to ensure the stability of target proteins or peptides, thereby enhancing the accuracy and reliability of assay results.
| Molecular weight | 489.62 |
|---|---|
| Linear formula | C21H40N6O4 · 1/2H2SO4 |
| Assay | ≥90% (HPLC) |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Propionyl-leupeptin hemisulfate salt used for?
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Propionyl-leupeptin hemisulfate salt is primarily used as a protease inhibitor, particularly for serine proteases, in biochemical research, cell biology, and neuroscience studies. It helps prevent protein degradation during experimental procedures.
What are the CAS number and formula for Propionyl-leupeptin hemisulfate salt?
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The CAS number is 24365-46-6 and the linear formula is C21H40N6O4 · 1/2H2SO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Propionyl-leupeptin hemisulfate salt with an assay of ≥90% (HPLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
What are the safety and handling recommendations for this product?
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When handling Propionyl-leupeptin hemisulfate salt, it is recommended to wear eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. The product has a WGK Germany rating of 3.
How is Propionyl-leupeptin hemisulfate salt stored and shipped?
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Propionyl-leupeptin hemisulfate salt should be stored at -20°C. TSS exports fine chemicals globally and ensures appropriate packaging and shipping conditions are met.
How can I request a sample or quote for Propionyl-leupeptin hemisulfate salt?
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Please contact our customer service team via phone or email to request a sample or obtain a quotation for Propionyl-leupeptin hemisulfate salt. Our team will assist you promptly.
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