(R)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis[bis(3,5-dimethylphenyl)phosphine]
(R)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis[bis(3,5-dimethylphenyl)phosphine], also known as (R)-3,5-Xyl-MeOBIPHEP, is a sophisticated atropisomeric phosphine ligand with CAS number 394248-45-4. Its molecular formula is C46H48O2P2 and it has a molecular weight of 694.82 g/mol. This chiral ligand is primarily employed in asymmetric synthesis, serving as a crucial component in the development of enantioselective catalytic processes.
- IUPAC
- (R)-2,2′-Bis[bis(3,5-dimethyl)phosphino]-6,6′-dimethoxy-1,1′-biphenyl,(R)-3,5-Xyl-MeOBIPHEP,SL-A120-1
- Synonyms
- (R)-3,5-Xyl-MeOBIPHEPSL-A120-1
![(R)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis[bis(3,5-dimethylphenyl)phosphine] (C46H48O2P2) — chemical structure, CAS 394248-45-4; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F394248-45-4.png&w=3840&q=75)
Asymmetric Catalysis
This MeOBIPHEP ligand is utilized in asymmetric catalysis to promote enantioselective transformations. It plays a key role in the synthesis of chiral molecules, enabling the preferential formation of one enantiomer over the other.
Chiral Ligand Development
As a privileged ligand, it is instrumental in the design and optimisation of catalytic systems for stereoselective reactions. Its unique atropisomeric structure contributes to high levels of stereocontrol in various chemical syntheses.
Pharmaceutical Intermediate Synthesis
The compound is valuable in the synthesis of complex organic molecules, including potential pharmaceutical intermediates. Its application aids in the efficient production of stereochemically pure compounds essential for drug discovery and development.
| Molecular weight | 694.82 |
|---|---|
| Empirical formula | C46H48O2P2 |
| Assay | ≥97% (CHN) |
| Optical purity | ee: ≥99% |
| Application | Atropisomeric MeOBIPHEP ligands |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis[bis(3,5-dimethylphenyl)phosphine] used for?
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This compound is primarily used as a chiral ligand in asymmetric synthesis and catalysis, particularly in enantioselective reactions for the creation of chiral molecules and pharmaceutical intermediates.
What is the CAS number and formula for this product?
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The CAS number is 394248-45-4 and the empirical formula is C46H48O2P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥97% (CHN) and an optical purity of ee: ≥99%. This is a research grade material and TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling considerations?
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When handling this chemical, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A respirator filter of type N95 (US) or P1 (EN143) is recommended. It is classified under WGK 2 in Germany, indicating a moderate hazard to water.
How is this product typically packed and shipped?
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This chemical is carefully packed to ensure safe transit and is available for export globally by Tech Serve Solutions.
How can I request a sample or a quote?
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To request a sample or obtain a quotation for (R)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis[bis(3,5-dimethylphenyl)phosphine], please contact the Tech Serve Solutions sales team via our website or direct inquiry channels.
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