(R)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis(diisopropylphosphine)
(R)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis(diisopropylphosphine), also known by its CAS number 150971-45-2, is a chiral phosphine ligand. With a molecular weight of 446.54 g/mol and an empirical formula of C26H40O2P2, this atropisomeric compound is a key component in asymmetric synthesis. It is particularly recognised for its role in catalysis, enabling enantioselective transformations essential for producing chiral molecules in the pharmaceutical and fine chemical industries.
- IUPAC
- (R)-2,2′-Bis(diisopropylphosphino)-6,6′-dimethoxy-1,1′-biphenyl,(R)-iPr-MeOBIPHEP,SL-A116-1
- Synonyms
- 150971-45-2C26H40O2P2(R)-2,2′-Bis(diisopropylphosphino)-6,6′-dimethoxy-1,1′-biphenyl(R)-iPr-MeOBIPHEPSL-A116-1
Asymmetric Catalysis
This atropisomeric MeOBIPHEP ligand is extensively employed in asymmetric catalysis, facilitating highly enantioselective reactions. Its structure allows for precise control over the stereochemical outcome of transformations, crucial for synthesising chiral pharmaceuticals and complex organic molecules.
Synthesis of Chiral Intermediates
It serves as a vital chiral auxiliary or ligand in the synthesis of enantiomerically pure intermediates. These intermediates are building blocks for active pharmaceutical ingredients (APIs) and other high-value fine chemicals where specific stereochemistry is critical for biological activity.
Ligand for Transition Metal Catalysis
As a privileged ligand, it forms active complexes with various transition metals, enhancing their catalytic performance in reactions such as hydrogenation, C-C coupling, and conjugate additions. This leads to improved yields and enantioselectivities.
| Molecular weight | 446.54 |
|---|---|
| Empirical formula | C26H40O2P2 |
| Assay | ≥97% |
| Optical purity | ee: ≥99% |
| Application | Atropisomeric MeOBIPHEP ligands |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis(diisopropylphosphine) used for?
+
This compound is primarily used as a chiral phosphine ligand in asymmetric catalysis and for the synthesis of chiral intermediates in the pharmaceutical and fine chemical industries.
What is the CAS number and formula for this chemical?
+
The CAS number is 150971-45-2, and its empirical formula is C26H40O2P2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this product with an assay of ≥97% and an optical purity of ee: ≥99%. We do not represent this product as USP, BP, or EP grade.
How should (R)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis(diisopropylphosphine) be handled?
+
Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound carries a WGK Germany hazard level of 3.
Is this chemical a controlled substance?
+
The provided data does not indicate that this chemical is a controlled substance.
How is this product packed and shipped?
+
This product is carefully packed according to industry standards to ensure safe transit and is exported globally by Tech Serve Solutions.
How can I request a sample or quote?
+
Please contact our sales team via the website or direct inquiry to request a sample or a formal quotation for this product.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis