(R)-(4-Fluorophenyl)oxirane
(R)-(4-Fluorophenyl)oxirane (CAS: 134356-73-3, C8H7FO) is a chiral fluorinated epoxide. With a molecular weight of 138.14 g/mol, it serves as a valuable building block in organic synthesis, particularly for introducing fluorinated chiral centres. Its epoxide functionality allows for diverse chemical transformations, making it useful in the development of complex molecules, including pharmaceutical intermediates and advanced materials. TSS supplies this chemical under a technical grade with a minimum assay of 90.0%.
- IUPAC
- (R)-4-Fluorostyrene oxide
- Synonyms
- (R)-4-Fluorostyrene oxide
Chiral Synthesis
This enantiomerically enriched epoxide is a key intermediate for asymmetric synthesis, enabling the stereoselective construction of chiral molecules. Its incorporation is vital in pathways requiring specific stereochemistry for biological activity.
Fluorinated Building Block
The presence of a fluorine atom imparts unique electronic and metabolic properties, making it an attractive component in the design of pharmaceuticals and agrochemicals. It allows for targeted modification of molecular properties.
Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs) where a fluorinated chiral moiety is required. Its reactive epoxide ring facilitates coupling with various nucleophiles.
Materials Science
Can be employed in the development of specialty polymers and advanced materials where the unique properties conferred by the fluorophenyl group are advantageous.
| Molecular weight | 138.14 |
|---|---|
| Empirical formula | C8H7FO |
| Assay | ≥90.0% (GC) |
| Grade | technical |
| Optical purity | enantiomeric ratio: ≥99.5:0.5 |
Hazard statements
- H225Highly flammable liquid and vapour
- H301Toxic if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 22 °C / 71.6 °F |
| Transport (UN / ADR) | UN 1992 3/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-21/22-36/37/38-40 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(4-Fluorophenyl)oxirane used for?
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(R)-(4-Fluorophenyl)oxirane is a chiral building block primarily used in asymmetric synthesis for the creation of fluorinated chiral molecules, including pharmaceutical intermediates and advanced materials.
What are the CAS number and formula for (R)-(4-Fluorophenyl)oxirane?
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The CAS number is 134356-73-3 and the molecular formula is C8H7FO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(4-Fluorophenyl)oxirane at a technical grade with an assay of ≥90.0% (GC) and an enantiomeric ratio of ≥99.5:0.5. We do not represent this product as USP, BP, or EP grade.
What are the main safety hazards associated with (R)-(4-Fluorophenyl)oxirane?
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(R)-(4-Fluorophenyl)oxirane is a highly flammable liquid and vapour (H225). It is toxic if swallowed (H301) and harmful in contact with skin (H312). It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). It is also suspected of causing cancer (H351). Strict adherence to safety protocols, including appropriate PPE (gloves, eyeshields, face shields, and respiratory protection), is essential.
How is (R)-(4-Fluorophenyl)oxirane packed, shipped, and exported?
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This product is packed and shipped in accordance with international regulations for hazardous materials, including UN 1992 (Flammable liquid, toxic, n.o.s.). Tech Serve Solutions is experienced in global export procedures.
How can I request a sample or a quote for (R)-(4-Fluorophenyl)oxirane?
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To request a sample or obtain a quotation, please contact our sales department via the website or direct email, providing your specific requirements and delivery details.
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