3,4-Dichlorobenzyl chloride
3,4-Dichlorobenzyl chloride (CAS: 102-47-6) is an organic compound with the molecular formula Cl2C6H3CH2Cl and a molecular weight of 195.47. This halogenated hydrocarbon serves as a valuable building block in organic synthesis. It is commonly employed in Friedel-Crafts reactions and as an alkylating agent in the development of advanced materials and complex organic molecules. Tech Serve Solutions supplies this chemical with an assay of 97%.
- IUPAC
- α,3,4-Trichlorotoluene
- Synonyms
- α,3,4-Trichlorotoluene
Intermediate for Sertraline Synthesis
3,4-Dichlorobenzyl chloride is utilised in the Friedel-Crafts synthesis of 4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenone, a critical intermediate in the multi-step production of the antidepressant sertraline.
Alkylation in Polymer Synthesis
This compound functions as an alkylating agent in the synthesis of poly(ether ketone)s. The resulting polymers feature pendant sulfonic acid groups, imparting desirable properties for various material science applications.
Preparation of Benzimidazole Derivatives
It is employed in the preparation of specific benzimidazole compounds, such as 5,6-dichloro-2-(3,4-dichlorobenzylthio)benzimidazole, for further chemical research and development.
| Molecular weight | 195.47 |
|---|---|
| Linear formula | Cl2C6H3CH2Cl |
| Assay | 97% |
| Boiling point | 122-124 °C/14 mmHg(lit.) |
| Density | 1.411 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.577(lit.) |
| Application | 3,4-Dichlorobenzyl chloride has been used:• in Friedel-Crafts synthesis of 4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenone, a key intermediate for the synthesis of sertraline1• as alkylating agent in synthesis of poly(ether ketone)s having pendant sulfonic acid groups2• in preparation of 5,6-dichloro-2-(3,4-dichlorobenzylthio)benzimidazole3 |
Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-36/37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-Dichlorobenzyl chloride used for?
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3,4-Dichlorobenzyl chloride is used as a key intermediate in organic synthesis, notably in the Friedel-Crafts reaction for producing sertraline intermediates and as an alkylating agent in polymer chemistry.
What is the CAS number and chemical formula for 3,4-Dichlorobenzyl chloride?
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The CAS number is 102-47-6, and the linear formula is Cl2C6H3CH2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,4-Dichlorobenzyl chloride with an assay of 97%. This is a technical grade material and is not represented as USP, BP, EP, or any other pharmacopoeia standard.
How should 3,4-Dichlorobenzyl chloride be handled safely?
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3,4-Dichlorobenzyl chloride is classified as Danger. It causes severe skin burns and eye damage and may cause respiratory irritation (H314, H335). Always handle with appropriate personal protective equipment, including gloves, eye protection (faceshields, goggles), and respiratory protection (type ABEK respirator filter or equivalent).
Is 3,4-Dichlorobenzyl chloride a controlled substance?
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The provided data does not indicate that 3,4-Dichlorobenzyl chloride is a controlled substance.
How is 3,4-Dichlorobenzyl chloride packed and shipped?
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3,4-Dichlorobenzyl chloride is shipped as UN 3265, Class 8, Packing Group II. Specific packaging details are available upon request.
How can I request a quote or sample?
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To request a quote or sample of 3,4-Dichlorobenzyl chloride, please contact our sales department via the website or direct inquiry.
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