(R)-(+)-1-Boc-2-pyrrolidinemethanol
(R)-(+)-1-Boc-2-pyrrolidinemethanol (CAS: 83435-58-9), with the molecular formula C10H19NO3 and a molecular weight of 201.26 g/mol, is a chiral amino alcohol derivative. It serves as a valuable building block in organic synthesis, particularly in the preparation of complex molecules and pharmaceuticals. Its stereochemistry and functional groups make it useful in stereoselective reactions and the development of novel chemical entities.
- IUPAC
- (R)-(+)-1-(tert-Butoxycarbonyl)-2-pyrrolidinemethanol,N-t-Boc-D-prolinol,N-Boc-D-prolinol
- Synonyms
- (R)-(+)-1-(tert-Butoxycarbonyl)-2-pyrrolidinemethanolN-t-Boc-D-prolinolN-Boc-D-prolinol
Chiral Building Block in Organic Synthesis
This compound acts as a versatile chiral synthon, enabling the stereocontrolled construction of complex organic molecules. Its pyrrolidine ring and protected amine functionality are useful in asymmetric synthesis strategies.
Pharmaceutical Intermediate
It is employed in the synthesis of active pharmaceutical ingredients (APIs), contributing to the development of new therapeutic agents. Its specific stereochemistry is often crucial for biological activity.
Peptide Chemistry
As an amino alcohol derivative, it finds application in peptide synthesis and the creation of peptidomimetics. It can be incorporated into peptide backbones or side chains to modify properties.
Chemical Biology Research
Used in research settings for probing biological pathways and developing chemical probes. Its structure can be modified to create molecules for studying biological systems.
| Molecular weight | 201.26 |
|---|---|
| Empirical formula | C10H19NO3 |
| Assay | 98% |
| Optical activity | [α]23/D +50°, c = 1.3 in chloroform |
| Melting point | 60-64 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-1-Boc-2-pyrrolidinemethanol used for?
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It is primarily used as a chiral building block in organic synthesis, a pharmaceutical intermediate, and in applications related to peptide chemistry and chemical biology.
What is the CAS number and formula for (R)-(+)-1-Boc-2-pyrrolidinemethanol?
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The CAS number is 83435-58-9 and the empirical formula is C10H19NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-1-Boc-2-pyrrolidinemethanol with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should (R)-(+)-1-Boc-2-pyrrolidinemethanol be handled?
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Based on GHS information, it may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Use a dust mask type N95 (US), safety-specific eyeshields, and gloves. Ensure good ventilation. Avoid breathing dust.
Is this chemical suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. This product can be packed and shipped internationally.
How can I request a sample or quote for (R)-(+)-1-Boc-2-pyrrolidinemethanol?
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Please contact our sales team via the website or by phone to request a sample or a quotation for this product.
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