(R)-(+)-1-Cbz-2-piperidinecarboxylic acid
(R)-(+)-1-Cbz-2-piperidinecarboxylic acid (CAS: 28697-09-8, C14H17NO4) is a chiral building block with a molecular weight of 263.29 g/mol. This compound is primarily utilised in asymmetric synthesis and general chemical synthesis, serving as a valuable heterocyclic intermediate. Its specific stereochemistry makes it a key component in the construction of complex chiral molecules for research and development purposes, particularly within pharmaceutical and fine chemical sectors.
- IUPAC
- N-Cbz-(R)-(+)-pipecolinic acid
- Synonyms
- N-Cbz-(R)-(+)-pipecolinic acid

Asymmetric Synthesis
This chiral piperidine derivative is employed as a stereospecific building block in the asymmetric synthesis of complex organic molecules. Its defined stereochemistry allows for the controlled introduction of chirality into target compounds.
Pharmaceutical Intermediate
Utilised as an intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a chiral piperidine core. Its structure is relevant for developing novel therapeutic agents.
Chemical Synthesis
Serves as a versatile reagent in general organic synthesis. It can be incorporated into various reaction pathways to construct heterocyclic scaffolds and introduce specific functional groups.
Research and Development
A valuable tool for academic and industrial research laboratories engaged in the discovery and development of new chemical entities and synthetic methodologies.
| Molecular weight | 263.29 |
|---|---|
| Empirical formula | C14H17NO4 |
| Assay | 97% |
| Optical activity | [α]20/D +60°, c = 2 in acetic acid |
| Melting point | 111-115 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-1-Cbz-2-piperidinecarboxylic acid used for?
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(R)-(+)-1-Cbz-2-piperidinecarboxylic acid is used in asymmetric synthesis and general chemical synthesis as a chiral building block and heterocyclic intermediate, particularly in the development of pharmaceuticals.
What is the CAS number and formula for (R)-(+)-1-Cbz-2-piperidinecarboxylic acid?
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The CAS number is 28697-09-8, and the empirical formula (Hill notation) is C14H17NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-1-Cbz-2-piperidinecarboxylic acid with a minimum assay of 97%. This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, EP, or any other pharmacopoeia grade.
How should (R)-(+)-1-Cbz-2-piperidinecarboxylic acid be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. This compound is a skin, eye, and respiratory irritant (H315-H319-H335).
Is (R)-(+)-1-Cbz-2-piperidinecarboxylic acid a controlled substance?
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Based on the provided data, (R)-(+)-1-Cbz-2-piperidinecarboxylic acid is not indicated as a controlled substance.
How is this chemical packed and exported?
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This chemical is exported by Tech Serve Solutions, a specialist global supplier. Packaging details are available upon request and are designed to maintain product integrity during transport.
How can I request a quote or sample?
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To request a quote or sample of (R)-(+)-1-Cbz-2-piperidinecarboxylic acid, please contact the Tech Serve Solutions sales team via the website or direct inquiry channels.
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