(R)-(+)-1-Octyn-3-ol

CAS 32556-70-0CH3(CH2)4CH(OH)C≡CHChemical Synthesis

(R)-(+)-1-Octyn-3-ol (CAS: 32556-70-0), with the molecular formula CH3(CH2)4CH(OH)C≡CH and a molar mass of 126.20 g/mol, is a chiral secondary alcohol. It is primarily utilised as a key intermediate in the synthesis of prostaglandins. This optically active compound serves as a valuable building block in asymmetric synthesis and organic chemistry research.

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(R)-(+)-1-Octyn-3-ol (CH3(CH2)4CH(OH)C≡CH) — chemical structure, CAS 32556-70-0; Chemistry, fine chemical supplied by Tech Serve Solutions

AlcoholsAsymmetric SynthesisChemical SynthesisChiral Building BlocksOrganic Building Blocks

01 /Applications

Prostaglandin Synthesis

Serves as a crucial intermediate in the laboratory synthesis of various prostaglandins, which are biologically active lipid compounds. Its chiral nature is essential for constructing the specific stereochemistry required for these complex molecules.

Asymmetric Synthesis

As a chiral building block, (R)-(+)-1-Octyn-3-ol is employed in asymmetric synthesis to introduce stereocentres in target molecules. This is vital for the development of enantiomerically pure pharmaceuticals and fine chemicals.

Organic Building Block

This compound functions as a versatile organic building block in complex molecule synthesis. Its combination of an alkyne and a chiral secondary alcohol functional group allows for diverse chemical transformations.

02 /Properties

Molecular weight	126.20
Linear formula	CH3(CH2)4CH(OH)C≡CH
Assay	99%
Boiling point	100 °C/20 mmHg(lit.)
Density	0.864 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.442(lit.)
Optical activity	[α]20/D +6.5°, c = 2 in methylene chloride
Optical purity	ee: 98% (GLC)
Application	Key intermediate for the synthesis of prostaglandins.1,2,3

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection

Protective equipment	Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	64 °C / 147.2 °F
Transport (UN / ADR)	UN 2810 6.1 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	20/21/22
Safety statements (S)	27-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

32556-70-0

MDL number

MFCD00192370

PubChem substance

24864835

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (R)-(+)-1-Octyn-3-ol used for?

(R)-(+)-1-Octyn-3-ol is used as a key intermediate in the synthesis of prostaglandins and as a chiral building block in asymmetric and organic synthesis.

What is the CAS number and molecular formula for (R)-(+)-1-Octyn-3-ol?

The CAS number is 32556-70-0 and the molecular formula is CH3(CH2)4CH(OH)C≡CH.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (R)-(+)-1-Octyn-3-ol with an assay of 99%. We do not represent this product as meeting any pharmacopoeia standards such as USP, BP, or EP.

How should (R)-(+)-1-Octyn-3-ol be handled safely?

(R)-(+)-1-Octyn-3-ol is harmful if swallowed, in contact with skin, or if inhaled. Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (e.g., ABEK type respirator filter), should be used. Handle in a well-ventilated area.