Hydantoin-5-acetic acid
Hydantoin-5-acetic acid (CAS: 5427-26-9, C5H6N2O4) is a key heterocyclic building block with a molecular weight of 158.11 g/mol. This compound serves as a valuable reactant in the synthesis of diverse organic molecules. Its applications span the development of antiparasitic agents, anticancer compounds, and anti-inflammatory drugs, underscoring its significance in medicinal chemistry and fine chemical synthesis.
- IUPAC
- 2,4-Dioxoimidazolidine-5-acetic acid,5-Hydantoinacetic acid,DL-5-(Carboxymethyl)hydantoin
- Synonyms
- 2,4-Dioxoimidazolidine-5-acetic acid5-Hydantoinacetic acidDL-5-(Carboxymethyl)hydantoin

Synthesis of Antiparasitic Agents
Hydantoin-5-acetic acid is a precursor for nonfolate compounds that function as antiparasitic agents. These molecules inhibit pteridine reductase, a vital enzyme in parasitic organisms.
Development of Anticancer Agents
It is utilised in the synthesis of 2,4-azolidinedione-acetic acid derivatives. These compounds have shown potential as anticancer agents, contributing to oncological research.
Preparation of Anti-inflammatory and Analgesic Drugs
This compound is employed as a reactant in the preparation of various anti-inflammatory and analgesic drugs, aiding in the development of pain management and anti-inflammatory therapies.
Amide Synthesis
Hydantoin-5-acetic acid can be used in the synthesis of amides. Specifically, it can be employed with polystyrene-supported N-hydroxybenxotriazole resin for this purpose.
| Molecular weight | 158.11 |
|---|---|
| Empirical formula | C5H6N2O4 |
| Assay | 98% |
| Application | Reactant for synthesis of:• Nonfolate compounds as antiparasitic agents inhibiting pteridine reductase1• 2,4-Azolidinedione-acetic acid derivatives as anticancer agents2• Anti-inflammatory and analgesic drugs3,4• Amides via polystyrene-supported N-hydroxybenxotriazole resin5 |
| Melting point | 214-215 °C (dec.)(lit.) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Hydantoin-5-acetic acid used for?
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Hydantoin-5-acetic acid is primarily used as a reactant in the synthesis of nonfolate antiparasitic agents, 2,4-azolidinedione-acetic acid derivatives with anticancer properties, anti-inflammatory and analgesic drugs, and amides.
What are the CAS number and molecular formula for Hydantoin-5-acetic acid?
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The CAS number for Hydantoin-5-acetic acid is 5427-26-9, and its molecular formula is C5H6N2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Hydantoin-5-acetic acid with an assay of 98%. This product is not supplied as USP, BP, or EP grade.
What are the safety and handling recommendations for Hydantoin-5-acetic acid?
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Hydantoin-5-acetic acid is classified under WGK 2 (Water Hazard Class 2) in Germany. Handle with appropriate personal protective equipment in a well-ventilated area. Consult the Safety Data Sheet (SDS) for detailed handling instructions.
How is Hydantoin-5-acetic acid packed, shipped, and exported?
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Hydantoin-5-acetic acid is carefully packed to ensure product integrity during transit and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for Hydantoin-5-acetic acid?
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To request a sample or a quote for Hydantoin-5-acetic acid, please contact the Tech Serve Solutions sales team through our website or by phone.
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