Homopiperazine
Homopiperazine (CAS: 505-66-8), with the molecular formula C5H12N2 and a molecular weight of 100.16 g/mol, is a heterocyclic organic compound. This diazacycloheptane derivative is primarily utilised as a versatile building block in chemical synthesis. Its structure lends itself to incorporation into more complex molecules, making it a valuable intermediate in the development of novel chemical entities within research and industrial settings.
- IUPAC
- 1,4-Diazacycloheptane,2,3,4,5,6,7-Hexahydro-1H-1,4-diazepine
- Synonyms
- 1,4-Diazacycloheptane2,3,4,5,6,7-Hexahydro-1H-1,4-diazepine

Organic Synthesis Intermediate
Homopiperazine serves as a crucial building block in organic chemistry, enabling the construction of diverse molecular frameworks. Its diamine structure allows for participation in a variety of coupling and condensation reactions.
Heterocyclic Chemistry
As a member of the piperazine family, homopiperazine is fundamental in the synthesis of more complex heterocyclic compounds. It is frequently employed in the creation of novel drug candidates and functional materials.
Research and Development
This compound is utilised in academic and industrial research laboratories for exploring new synthetic pathways and developing novel chemical entities. Its specific structural features make it an interesting reagent for medicinal chemistry exploration.
| Molecular weight | 100.16 |
|---|---|
| Empirical formula | C5H12N2 |
| Assay | ≥98.0% (NT) |
| Boiling point | 169 °C(lit.) |
| Melting point | 38-40 °C(lit.)38-41 °C |


Hazard statements
- H311Toxic in contact with skin
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 61 °C / 141.8 °F |
| Transport (UN / ADR) | UN 3259PSN1 8 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | C |
| Risk statements (R) | 21-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Homopiperazine (CAS 505-66-8) used for?
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Homopiperazine (CAS 505-66-8) is primarily used as a versatile building block in organic synthesis and heterocyclic chemistry for research and development purposes.
What are the CAS number and molecular formula for Homopiperazine?
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The CAS number for Homopiperazine is 505-66-8, and its molecular formula is C5H12N2.
What grade and purity does Tech Serve Solutions supply for Homopiperazine?
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Tech Serve Solutions supplies Homopiperazine with an assay of ≥98.0% (NT). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should Homopiperazine be handled safely?
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Homopiperazine is classified as dangerous. It is harmful in contact with skin and causes severe skin burns and eye damage. Appropriate personal protective equipment, including eyeshields, face shields, and chemically resistant gloves, must be worn. Handle in a well-ventilated area or under a fume hood, and follow all safety statements (P280, P305 + P351 + P338, P310).
Is Homopiperazine a controlled substance?
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The provided data does not indicate that Homopiperazine (CAS 505-66-8) is a controlled substance.
How is Homopiperazine packed, shipped, or exported?
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Homopiperazine is packed and shipped in compliance with transport regulations (UN 3259, PSN1 8 / PGII). As a global supplier, Tech Serve Solutions handles all necessary export documentation and procedures.
How can I request a quote or sample of Homopiperazine?
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To request a quote or sample of Homopiperazine, please contact our sales department through the TSS website or by phone, providing your specific requirements and shipping details.
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