Homogentisic acid
Homogentisic acid (CAS 451-13-8) is an organic compound with the linear formula (HO)2C6H3CH2CO2H and a molecular weight of 168.15 g/mol. This off-white to tan crystalline solid is known for its role as a key metabolite in tyrosine catabolism. It serves as a valuable building block in chemical synthesis and is relevant in biochemical research, particularly in the study of metabolic pathways.
- IUPAC
- 2,5-Dihydroxyphenylacetic acid
- Synonyms
- 2,5-Dihydroxyphenylacetic acid
Biochemical Research
Homogentisic acid is utilized in studies of metabolic pathways and enzyme function, especially concerning tyrosine metabolism. Its presence and metabolism are central to understanding certain genetic disorders.
Chemical Synthesis
As an organic building block, it can be employed in the synthesis of more complex molecules. Its specific functional groups, a carboxylic acid and two hydroxyl groups on an aromatic ring, offer versatile reaction sites.
Metabolomics Studies
This compound is a significant analyte in metabolomics, aiding researchers in identifying and quantifying metabolites involved in cellular processes. It is a key component for understanding metabolic profiling.
| Molecular weight | 168.15 |
|---|---|
| Linear formula | (HO)2C6H3CH2CO2H |
| Form | crystalline |
| Colour | off-white to tan |
| Storage temperature | 2-8°C |
| Melting point | 150-152 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Homogentisic acid used for?
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Homogentisic acid is used in biochemical research, particularly for studying metabolic pathways and enzyme function related to tyrosine metabolism. It also serves as an organic building block in chemical synthesis and is an analyte in metabolomics studies.
What are the CAS number and chemical formula for Homogentisic acid?
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The CAS number for Homogentisic acid is 451-13-8, and its linear formula is (HO)2C6H3CH2CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Homogentisic acid in a crystalline form with an off-white to tan colour. The specific assay or purity is available upon request, and it is supplied for research and laboratory use; it is not represented as USP, BP, or EP grade.
How should Homogentisic acid be handled and stored?
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Homogentisic acid should be handled with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. It is irritating to the eyes, respiratory system, and skin (H315, H319, H335). Store at 2-8°C.
Is Homogentisic acid available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Homogentisic acid, facilitating international orders.
How can I request a sample or quote for Homogentisic acid?
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To request a sample or quote for Homogentisic acid, please contact our sales team through the website or by phone.
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