Histamine
Histamine (CAS 51-45-6, C5H9N3) is a biogenic amine with a molecular weight of 111.15 g/mol. It is a key signalling molecule in the human body, particularly involved in local immune responses, and the regulation of physiological functions in the gut and brain. Histamine is also a significant neurotransmitter. TSS supplies this compound for research and chemical synthesis applications, adhering to strict quality controls.
- IUPAC
- 2-(4-Imidazolyl)ethylamine
- Synonyms
- 2-(4-Imidazolyl)ethylamine
Neurotransmitter Research
Histamine acts as a neurotransmitter in the central nervous system, playing roles in wakefulness, appetite, and cognitive functions. Its study is crucial for understanding neurological disorders.
Allergy and Immunology Studies
As a mediator of inflammatory responses, histamine is central to allergic reactions and immune system signalling. Research using histamine helps in developing anti-allergy treatments.
Pharmacological Research
Histamine and its receptors are targets for numerous pharmaceuticals, including antihistamines. Studying histamine provides insights into drug development for various conditions.
Chemical Synthesis
This imidazole derivative serves as a versatile building block in organic synthesis for creating more complex molecules, including potential drug candidates.
| Molecular weight | 111.15 |
|---|---|
| Empirical formula | C5H9N3 |
| Assay | ≥97.0% (NT) |
| Boiling point | 167 °C/0.8 mmHg(lit.) |
| Storage temperature | −20°C |
| Melting point | 83-84 °C(lit.)~84 °C |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38-42/43 |
| Safety statements (S) | 22-26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Histamine used for?
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Histamine is used in research for studying neurotransmission, immune responses, allergic reactions, and as a building block in chemical synthesis. It is not intended for human or animal consumption.
What is the CAS number and formula for Histamine?
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The CAS number for Histamine is 51-45-6, and its molecular formula is C5H9N3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Histamine with a purity of ≥97.0% (NT). This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should Histamine be handled and stored?
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Histamine is classified as acutely toxic and an irritant. Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shields, and gloves. Avoid dust formation and inhalation. Store in a cool, dry place at -20°C.
Is Histamine a controlled substance?
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Based on the provided data, Histamine (CAS 51-45-6) is not indicated as a controlled substance in most jurisdictions, but users should always verify local regulations.
How is Histamine packed, shipped, and exported?
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Histamine is packed according to UN 2811, Hazard Class 6.1, Packing Group III for international shipping. TSS is experienced in exporting chemicals globally.
How can I request a sample or quote for Histamine?
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To request a sample or a quote for Histamine, please contact the TSS sales team via our website or direct inquiry channels, providing your specific requirements.
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