2-Bromo-1,1-dimethoxyethane
2-Bromo-1,1-dimethoxyethane (CAS: 7252-83-7), also known as bromoacetaldehyde dimethyl acetal, is an organic compound with the linear formula BrCH2CH(OCH3)2 and a molecular weight of 169.02 g/mol. This chemical serves as a valuable building block in organic synthesis. It is primarily utilised in the preparation of various organic molecules, offering a reactive bromine atom and a protected aldehyde functionality for selective chemical transformations.
- IUPAC
- Bromoacetaldehyde dimethyl acetal
- Synonyms
- BrCH2CH(OCH3)2Bromoacetaldehyde dimethyl acetal
Organic Synthesis Intermediate
2-Bromo-1,1-dimethoxyethane is employed as a key intermediate in the synthesis of more complex organic structures. Its unique combination of a reactive alkyl bromide and a masked aldehyde allows for diverse synthetic strategies in academic and industrial research.
Preparation of Acetals
This compound has been used in the synthesis of specific acetals, such as 2,3-O-acetal, through reactions with diols under acidic catalysis, demonstrating its utility in protective group chemistry and the formation of cyclic structures.
Building Block for Heterocycles
The reactivity profile of 2-Bromo-1,1-dimethoxyethane makes it suitable for constructing various heterocyclic compounds, which are important scaffolds in medicinal chemistry and materials science.
| Molecular weight | 169.02 |
|---|---|
| Linear formula | BrCH2CH(OCH3)2 |
| Assay | 97% |
| Boiling point | 148-150 °C(lit.) |
| Density | 1.43 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.445(lit.) |
| Storage temperature | 2-8°C |
| Contains / stabiliser | 0.2% potassium carbonate as stabilizer |
| Application | 2-Bromo-1,1-dimethoxyethane (Bromoacetaldehyde dimethyl acetal) was used in the synthesis of 2,3-O-acetal via reaction with 2,3-diol in the presence of 10-camphorsulphonic acid (CSA)1. |
Hazard statements
- H226Flammable liquid and vapour
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 51 °C / 123.8 °F |
| Transport (UN / ADR) | UN 1989C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36 |
| Safety statements (S) | 26-36/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-1,1-dimethoxyethane used for?
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2-Bromo-1,1-dimethoxyethane is primarily used as a building block and intermediate in organic synthesis, including the preparation of acetals and heterocyclic compounds.
What is the CAS number and chemical formula for 2-Bromo-1,1-dimethoxyethane?
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The CAS number is 7252-83-7, and its linear formula is BrCH2CH(OCH3)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromo-1,1-dimethoxyethane with a minimum purity of 97%. We do not represent this product as USP, BP, or EP grade.
How should 2-Bromo-1,1-dimethoxyethane be handled safely?
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2-Bromo-1,1-dimethoxyethane is flammable and causes serious eye irritation. Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, in a well-ventilated area. Avoid exposure to heat, sparks, and open flames.
Is this chemical packed and shipped internationally by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and we can arrange for the packing and shipment of 2-Bromo-1,1-dimethoxyethane worldwide.
How can I request a sample or quote for 2-Bromo-1,1-dimethoxyethane?
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To request a sample or a quotation, please contact our sales team through the website or call us directly with your specific requirements.
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