2-Biphenylboronic acid
2-Biphenylboronic acid (CAS 4688-76-0), with the molecular formula C<sub>6</sub>H<sub>5</sub>C<sub>6</sub>H<sub>4</sub>B(OH)<sub>2</sub> and a molecular weight of 198.03 g/mol, is an organoboron compound. It functions as a versatile substrate in palladium-catalyzed cross-coupling reactions, notably enabling the synthesis of diarylmethanes when reacted with benzylic acetates. This compound is valuable for organic synthesis and the development of complex molecules.
Suzuki-Miyaura Coupling Reagent
2-Biphenylboronic acid is a key building block in Suzuki-Miyaura cross-coupling reactions. It facilitates the formation of new carbon-carbon bonds, essential for constructing complex organic frameworks used in pharmaceuticals and materials science.
Synthesis of Diaryl Methanes
This boronic acid serves as a substrate in palladium-catalyzed coupling reactions with benzylic acetates. This specific application leads to the efficient synthesis of diarylmethane structures, which are important motifs in medicinal chemistry.
Organic Synthesis Intermediate
As an aryl boronic acid derivative, it is widely employed in general organic synthesis. Its reactivity allows for the introduction of the biphenyl moiety into various molecular architectures.
| Molecular weight | 198.03 |
|---|---|
| Linear formula | C6H5C6H4B(OH)2 |
| Application | Substrate employed in a palladium-catalyzed cross-coupling with benzylic acetates providing diarylmethanes.8 |
| Melting point | 167-172 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Biphenylboronic acid used for?
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2-Biphenylboronic acid is primarily used as a substrate in palladium-catalyzed cross-coupling reactions, particularly for the synthesis of diarylmethanes. It is a valuable reagent in organic synthesis and the construction of complex molecules.
What is the CAS number and formula for 2-Biphenylboronic acid?
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The CAS number is 4688-76-0 and the linear formula is C<sub>6</sub>H<sub>5</sub>C<sub>6</sub>H<sub>4</sub>B(OH)<sub>2</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Biphenylboronic acid typically for research and chemical synthesis applications. The specific assay and purity are detailed on the product's Certificate of Analysis. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 2-Biphenylboronic acid be handled?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. Refer to the Safety Data Sheet for comprehensive handling and safety information. It is classified under WGK 3 in Germany.
Is 2-Biphenylboronic acid a controlled substance?
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The provided data does not indicate that 2-Biphenylboronic acid is a controlled substance.
How is 2-Biphenylboronic acid packed and shipped?
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Tech Serve Solutions exports fine chemicals globally. Packaging is designed to ensure product integrity and safety during transit. Please contact us for specific shipping and export details.
How can I request a sample or quote for 2-Biphenylboronic acid?
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To request a sample or a quotation, please use the 'Request Quote' or 'Sample Request' form on our website, or contact our sales team directly with your specific requirements.
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