2-Biphenylmagnesium bromide solution
2-Biphenylmagnesium bromide solution (CAS: 82214-69-5) is an organometallic reagent featuring a biphenyl group attached to a magnesium bromide moiety. With a molecular weight of 257.41 g/mol and supplied as a 0.5 M solution in diethyl ether, this compound is primarily utilised in organic synthesis. It serves as a versatile tool for introducing the biphenyl group into various organic molecules through Grignard reactions and related coupling chemistries.
Grignard Reagent in Organic Synthesis
As a Grignard reagent, 2-Biphenylmagnesium bromide solution is employed to form new carbon-carbon bonds. It reacts with electrophiles such as aldehydes, ketones, esters, and epoxides to create more complex organic structures.
Arylation Reactions
This reagent is effective for the arylation of various substrates, facilitating the introduction of the biphenyl moiety into pharmaceutical intermediates, agrochemicals, and materials science compounds.
Synthesis of Organobiphenyl Compounds
It is a key precursor for synthesising a range of organobiphenyl compounds, which are important structural motifs in areas like liquid crystals and organic light-emitting diodes (OLEDs).
| Molecular weight | 257.41 |
|---|---|
| Linear formula | C6H5C6H4MgBr |
| Density | 0.800 g/mL at 25 °C(lit.) |
| Concentration | 0.5 M in diethyl ether |
Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H336May cause drowsiness or dizziness
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | -40 °C / -40 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-19-22-34-67 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Biphenylmagnesium bromide solution used for?
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2-Biphenylmagnesium bromide solution (CAS: 82214-69-5) is used as a Grignard reagent in organic synthesis for introducing the biphenyl group into organic molecules and for arylation reactions.
What is the CAS number and formula for 2-Biphenylmagnesium bromide solution?
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The CAS number is 82214-69-5. The linear formula is C<sub>6</sub>H<sub>5</sub>C<sub>6</sub>H<sub>4</sub>MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 0.5 M solution in diethyl ether. We do not assign pharmacopoeia grades (USP, EP, BP) unless explicitly stated in the product data; this is a technical/research grade material.
How should 2-Biphenylmagnesium bromide solution be handled safely?
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This compound is highly flammable (Flash point -40 °C) and reacts violently with water. It is corrosive and can cause severe skin burns and eye damage. Handle in a well-ventilated area, away from ignition sources, and wear appropriate protective equipment, including gloves, eye protection, and protective clothing. May form explosive peroxides.
Is 2-Biphenylmagnesium bromide solution available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Biphenylmagnesium bromide solution, adhering to international shipping regulations.
How can I request a sample or quote?
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To request a sample or a quote for 2-Biphenylmagnesium bromide solution, please contact our sales team through the website or by phone, providing your specific requirements.
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