2,2-Dimethyl-N-(3-trimethylsilanylethynyl-pyridin-2-yl)-propionamide
2,2-Dimethyl-N-(3-trimethylsilanylethynyl-pyridin-2-yl)-propionamide (CAS: 499193-46-3) is a chemical compound with the molecular formula C15H22N2OSi and a molecular weight of 274.43 g/mol. It serves as a valuable building block in chemical synthesis, particularly within the realm of heterocyclic chemistry and organosilicon compounds. Its structure incorporates a pyridine core functionalised with a trimethylsilanylethynyl group and a propionamide moiety, making it suitable for diverse synthetic transformations.
- Synonyms
- C15H22N2OSi

Heterocyclic Synthesis
This compound is employed as a key intermediate in the construction of complex heterocyclic ring systems. The presence of the pyridine ring and reactive functional groups allows for its incorporation into various synthetic pathways.
Organosilicon Chemistry
The trimethylsilyl (TMS) group offers unique reactivity and handling properties, making this molecule useful in reactions involving organosilicon reagents. It can participate in cross-coupling reactions or serve as a protecting group.
Pharmaceutical Intermediates
As a pyridine derivative, it holds potential as a building block for the synthesis of active pharmaceutical ingredients (APIs) or related drug discovery research compounds.
Materials Science Research
The specific arrangement of functional groups may lend itself to applications in the development of novel organic materials with tailored electronic or optical properties.
| Molecular weight | 274.43 |
|---|---|
| Empirical formula | C15H22N2OSi |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2-Dimethyl-N-(3-trimethylsilanylethynyl-pyridin-2-yl)-propionamide used for?
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This compound is primarily used as a building block in chemical synthesis, particularly for creating heterocyclic structures and in organosilicon chemistry. It also finds application as an intermediate in pharmaceutical research and potentially in materials science.
What is the CAS number and formula for this product?
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The CAS number is 499193-46-3, and the empirical formula is C15H22N2OSi.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research chemical. The exact grade and purity are available upon request and are suitable for laboratory research and chemical synthesis. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 2,2-Dimethyl-N-(3-trimethylsilanylethynyl-pyridin-2-yl)-propionamide be handled?
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Specific safety data is provided in the Safety Data Sheet (SDS). General laboratory precautions should be observed, including appropriate personal protective equipment (gloves, eye protection) and handling in a well-ventilated area. Avoid contact with skin, eyes, and clothing.
Is this compound a controlled substance?
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Based on the provided data, there is no indication that this compound is a controlled substance. However, users should always comply with local and international regulations regarding chemical handling and procurement.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions ensures secure and compliant packaging for all its chemicals. We offer worldwide export services adhering to international shipping regulations for fine chemicals and laboratory reagents.
How can I request a sample or quote?
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To request a sample or obtain a quotation, please visit the product page on our website or contact our sales department directly. Provide the product name and CAS number (499193-46-3) for prompt service.
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