Zoledronic acid monohydrate
Zoledronic acid monohydrate (CAS: 165800-06-6), with the molecular formula C5H10N2O7P2·H2O and a molecular weight of 290.10, is supplied as a white to beige powder. This bisphosphonate is primarily utilised in biochemical research, particularly within cancer metabolism and cell biology studies. Its applications span investigations into kinase regulation and phospholipid metabolism, making it a valuable tool for understanding complex cellular signalling pathways.
- IUPAC
- P,P′-[1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid monohydrate,Zoledronate monohydrate,[1-hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid) monohydrate
- Synonyms
- P,P′-[1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid monohydrateZoledronate monohydrate[1-hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid) monohydrate

Cancer Research
Zoledronic acid monohydrate serves as a research chemical for investigating cancer metabolism and cell signalling pathways. It is employed in studies related to the mevalonate pathway and its role in cancer progression.
Biochemical Research Tool
This compound is utilized in cell biology research to study processes such as kinase regulation and phospholipid metabolism. It can be applied in experiments investigating cellular responses and signalling cascades.
Pharmacological Studies
As a bisphosphonate, it is used in research settings to explore mechanisms relevant to bone resorption and related cellular activities, providing insights for potential therapeutic avenues.
| Molecular weight | 290.10 |
|---|---|
| Empirical formula | C5H10N2O7P2·H2O |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | H2O: ≥2 mg/mL |
| Storage temperature | 2-8°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccatedprotect from light |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Zoledronic acid monohydrate primarily used for?
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Zoledronic acid monohydrate is primarily used as a research chemical in areas such as cancer metabolism, cell biology, and biochemical studies investigating kinase regulation and phospholipid metabolism.
What are the CAS number and molecular formula for Zoledronic acid monohydrate?
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The CAS number for Zoledronic acid monohydrate is 165800-06-6, and its molecular formula is C5H10N2O7P2·H2O.
What grade and purity does Tech Serve Solutions supply for Zoledronic acid monohydrate?
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Tech Serve Solutions supplies Zoledronic acid monohydrate with a purity of ≥98% as determined by HPLC. This product is intended for research and laboratory use, and TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades.
How should Zoledronic acid monohydrate be handled and stored?
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Zoledronic acid monohydrate is classified as a Warning substance (GHS07) and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area. Store desiccated and protected from light at 2-8°C.
Is Zoledronic acid monohydrate a controlled substance?
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The provided data does not indicate that Zoledronic acid monohydrate is a controlled substance.
How is Zoledronic acid monohydrate packed, shipped, and exported?
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Zoledronic acid monohydrate is carefully packed to maintain its stability and integrity during transit. As a global supplier, Tech Serve Solutions exports this chemical worldwide, adhering to all relevant shipping regulations.
How can I request a sample or obtain a quote for Zoledronic acid monohydrate?
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To request a sample or obtain a quotation for Zoledronic acid monohydrate, please contact the Tech Serve Solutions sales department via our website or directly by phone.
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