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Kainic acid monohydrate

CAS 58002-62-3C10H15NO4 · H2OCell Biology

Kainic acid monohydrate (CAS: 58002-62-3) is a water-soluble organic compound with the formula C10H15NO4 · H2O and a molecular weight of 231.25 g/mol. It is a potent excitotoxin and an agonist of AMPA and kainate receptors. Primarily utilized in neuroscience research, it serves as a tool to study excitotoxicity, epilepsy mechanisms, and neuronal cell death pathways.

IUPAC
2-Carboxy-3-carboxymethyl-4-isopropenylpyrrolidine
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Kainic acid monohydrate (C10H15NO4 · H2O) — chemical structure, CAS 58002-62-3; Life Science, fine chemical supplied by Tech Serve Solutions
AMPA/Kainate AgonistsAlgaeBioactive Small MoleculesCell BiologyExcitatory Amino AcidsIon ChannelsLigand-Gated Ion ChannelsNeuroscienceNeurotransmissionNeurotransmitters
01 /Applications

Neuroscience Research Tool

Kainic acid monohydrate is extensively used as a research chemical to induce excitotoxicity in animal models. This allows scientists to investigate the mechanisms of neuronal damage and cell death, particularly in conditions resembling epilepsy and other neurological disorders.

Epilepsy and Neurodegeneration Studies

The compound helps researchers understand the role of excitatory amino acid receptors in the pathogenesis of epilepsy. By selectively activating specific glutamate receptors, it facilitates the study of excitation-induced apoptosis and neurodegenerative processes.

Receptor Agonist Studies

As a specific agonist for AMPA and kainate subtypes of ionotropic glutamate receptors, it is employed to probe receptor function, signaling pathways, and their involvement in synaptic transmission and plasticity.

02 /Properties
Molecular weight231.25
Empirical formulaC10H15NO4 · H2O
Assay≥99% (TLC)
SolubilityH2O: soluble
Storage temperature2-8°C
Impurities testedGlutamate, free
ApplicationKainic acid is used to study mechanisms of excitation-induced apoptosis and epilepsy.
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
58002-62-3
MDL number
MFCD00150833
PubChem substance
24277985
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Kainic acid monohydrate primarily used for?

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Kainic acid monohydrate is primarily used as a research tool in neuroscience to study mechanisms of excitation-induced apoptosis, epilepsy, and excitotoxicity by acting as an agonist for AMPA and kainate receptors.

What is the CAS number and chemical formula for Kainic acid monohydrate?

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The CAS number for Kainic acid monohydrate is 58002-62-3, and its chemical formula is C10H15NO4 · H2O.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Kainic acid monohydrate with a purity of ≥99% (TLC). This product is intended for research and laboratory use and is not supplied as USP, BP, or EP grade.

How should Kainic acid monohydrate be handled safely?

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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. Refer to the safety data sheet for comprehensive handling guidelines.

Is Kainic acid monohydrate a controlled substance?

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The provided data does not indicate that Kainic acid monohydrate is a controlled substance.

How is Kainic acid monohydrate shipped and exported?

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Tech Serve Solutions is a global supplier and exporter of fine chemicals, capable of shipping and exporting Kainic acid monohydrate to research institutions worldwide.

How can I request a quote or sample for Kainic acid monohydrate?

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Please contact our sales team via the website or direct inquiry channels to request a quote or a sample of Kainic acid monohydrate.

Need Kainic acid monohydrate in a specific grade or volume?