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(R)-(+)-1-Boc-3-aminopyrrolidine

CAS 147081-49-0C9H18N2O2Chemical Synthesis

(R)-(+)-1-Boc-3-aminopyrrolidine (CAS: 147081-49-0, C9H18N2O2) is a chiral heterocyclic compound with a molecular weight of 186.25 g/mol. It is a valuable building block in asymmetric synthesis and chemical research. Its protected amine functionality and chiral pyrrolidine core make it suitable for constructing complex organic molecules and pharmaceutical intermediates.

IUPAC
(R)-(+)-N-Boc-3-aminopyrrolidine
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(R)-(+)-1-Boc-3-aminopyrrolidine (C9H18N2O2) — chemical structure, CAS 147081-49-0; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral Building BlocksHeterocyclic Building BlocksPyrrolidines
01 /Applications

Chiral Building Block

(R)-(+)-1-Boc-3-aminopyrrolidine serves as a key chiral synthon in the stereoselective synthesis of complex organic molecules. Its inherent chirality allows for the introduction of specific stereocenters in target compounds.

Pharmaceutical Intermediate Synthesis

This compound is utilised in the development of pharmaceutical agents. Its structure is amenable to further functionalization, facilitating the creation of novel drug candidates and active pharmaceutical ingredients (APIs).

Asymmetric Synthesis

In asymmetric synthesis, it acts as a chiral auxiliary or precursor for creating enantiomerically enriched products. It is particularly useful in constructing molecules with defined stereochemistry.

Heterocyclic Chemistry Research

Its pyrrolidine core makes it a useful starting material for exploring new heterocyclic compounds. Researchers utilise it in academic and industrial settings for novel molecule discovery.

02 /Properties
Molecular weight186.25
Empirical formulaC9H18N2O2
Assay97%
Boiling point243-244 °C(lit.)
Density1.098 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.472(lit.)
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Toxic (GHS06)
Toxic
Danger

Hazard statements

  • H301Toxic if swallowed
  • H318Causes serious eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P301IF SWALLOWED
  • P305IF IN EYES
Protective equipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point91 °C / 195.8 °F
Transport (UN / ADR)UN 2810 6.1 / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)22-41-44
Safety statements (S)26-36/37/39
Supplemental hazardsRisk of explosion if heated under confinement.

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
147081-49-0
MDL number
MFCD03419272
PubChem substance
24883312
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (R)-(+)-1-Boc-3-aminopyrrolidine used for?

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It is primarily used as a chiral building block and intermediate in asymmetric synthesis and the development of pharmaceutical agents.

What are the CAS number and formula for (R)-(+)-1-Boc-3-aminopyrrolidine?

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The CAS number is 147081-49-0, and its empirical formula is C9H18N2O2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (R)-(+)-1-Boc-3-aminopyrrolidine with an assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.

How should (R)-(+)-1-Boc-3-aminopyrrolidine be handled safely?

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This compound is classified as Danger, with hazards including H301 (Toxic if swallowed) and H318 (Causes serious eye damage). It also carries a risk of explosion if heated under confinement. Appropriate personal protective equipment, including eyeshields, faceshields, and suitable gloves and respirators, must be used. Refer to the Safety Data Sheet for full handling information.

How is (R)-(+)-1-Boc-3-aminopyrrolidine packed and shipped?

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Tech Serve Solutions exports chemicals globally, adhering to all relevant shipping regulations. Packing is done to ensure product integrity and safety during transit.

How can I request a sample or quote for (R)-(+)-1-Boc-3-aminopyrrolidine?

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Please contact our sales team via the website or by phone to request a sample or a quotation for (R)-(+)-1-Boc-3-aminopyrrolidine.

Need (R)-(+)-1-Boc-3-aminopyrrolidine in a specific grade or volume?