(R)-(+)-1-Boc-3-aminopyrrolidine
(R)-(+)-1-Boc-3-aminopyrrolidine (CAS: 147081-49-0, C9H18N2O2) is a chiral heterocyclic compound with a molecular weight of 186.25 g/mol. It is a valuable building block in asymmetric synthesis and chemical research. Its protected amine functionality and chiral pyrrolidine core make it suitable for constructing complex organic molecules and pharmaceutical intermediates.
- IUPAC
- (R)-(+)-N-Boc-3-aminopyrrolidine

Chiral Building Block
(R)-(+)-1-Boc-3-aminopyrrolidine serves as a key chiral synthon in the stereoselective synthesis of complex organic molecules. Its inherent chirality allows for the introduction of specific stereocenters in target compounds.
Pharmaceutical Intermediate Synthesis
This compound is utilised in the development of pharmaceutical agents. Its structure is amenable to further functionalization, facilitating the creation of novel drug candidates and active pharmaceutical ingredients (APIs).
Asymmetric Synthesis
In asymmetric synthesis, it acts as a chiral auxiliary or precursor for creating enantiomerically enriched products. It is particularly useful in constructing molecules with defined stereochemistry.
Heterocyclic Chemistry Research
Its pyrrolidine core makes it a useful starting material for exploring new heterocyclic compounds. Researchers utilise it in academic and industrial settings for novel molecule discovery.
| Molecular weight | 186.25 |
|---|---|
| Empirical formula | C9H18N2O2 |
| Assay | 97% |
| Boiling point | 243-244 °C(lit.) |
| Density | 1.098 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.472(lit.) |


Hazard statements
- H301Toxic if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 91 °C / 195.8 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41-44 |
| Safety statements (S) | 26-36/37/39 |
| Supplemental hazards | Risk of explosion if heated under confinement. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-1-Boc-3-aminopyrrolidine used for?
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It is primarily used as a chiral building block and intermediate in asymmetric synthesis and the development of pharmaceutical agents.
What are the CAS number and formula for (R)-(+)-1-Boc-3-aminopyrrolidine?
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The CAS number is 147081-49-0, and its empirical formula is C9H18N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-1-Boc-3-aminopyrrolidine with an assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should (R)-(+)-1-Boc-3-aminopyrrolidine be handled safely?
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This compound is classified as Danger, with hazards including H301 (Toxic if swallowed) and H318 (Causes serious eye damage). It also carries a risk of explosion if heated under confinement. Appropriate personal protective equipment, including eyeshields, faceshields, and suitable gloves and respirators, must be used. Refer to the Safety Data Sheet for full handling information.
How is (R)-(+)-1-Boc-3-aminopyrrolidine packed and shipped?
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Tech Serve Solutions exports chemicals globally, adhering to all relevant shipping regulations. Packing is done to ensure product integrity and safety during transit.
How can I request a sample or quote for (R)-(+)-1-Boc-3-aminopyrrolidine?
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Please contact our sales team via the website or by phone to request a sample or a quotation for (R)-(+)-1-Boc-3-aminopyrrolidine.
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