4-Aminopyridine
4-Aminopyridine (CAS: 504-24-5, C5H6N2) is a heterocyclic organic compound with a molecular weight of 94.11 g/mol. Available from Tech Serve Solutions with an assay of ≥99%, it is recognised for its role as a potassium channel blocker. This compound serves as a valuable building block in chemical synthesis and finds applications in research settings, particularly within cell biology and neuroscience, for studying ion channel function.
- IUPAC
- 4-Pyridinamine,4-Pyridylamine,4AP,Fampridine
- Synonyms
- 4-Pyridinamine4-Pyridylamine4APFampridine

Chemical Synthesis
4-Aminopyridine is utilised as a heterocyclic building block in the synthesis of more complex organic molecules. Its pyridine ring structure and amino group offer reactive sites for various chemical transformations.
Neuroscience Research
As a potassium channel modulator, 4-Aminopyridine is employed in neurological research to investigate the function of voltage-gated ion channels. It helps in understanding neuronal excitability and signal transmission.
Cell Biology Studies
This compound is used in cell biology research to probe ion channel activity and its effects on cellular processes. Its specific action on ion channels makes it a useful tool for studying cellular signalling pathways.
| Molecular weight | 94.11 |
|---|---|
| Empirical formula | C5H6N2 |
| Assay | ≥99% |
| Boiling point | 273 °C(lit.) |
| Solubility | DMF: soluble(lit.)DMSO: soluble(lit.)THF: soluble(lit.)acetone: soluble(lit.)acetonitrile: soluble(lit.)ethanol: soluble(lit.)isopropanol: soluble(lit.)methanol: soluble(lit.)water: soluble(lit.) |
| Melting point | 155-158 °C(lit.) |

Hazard statements
- H300Fatal if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P264Wash thoroughly after handling
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2671 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 28-36/37/38 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | mouse ... Kcna3(16491)rat ... Grin2a(24409) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Aminopyridine used for?
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4-Aminopyridine is primarily used as a potassium channel blocker in neuroscience and cell biology research, and as a building block in chemical synthesis.
What is the CAS number and formula for 4-Aminopyridine?
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The CAS number for 4-Aminopyridine is 504-24-5, and its chemical formula is C5H6N2.
What grade and purity does Tech Serve Solutions supply for 4-Aminopyridine?
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Tech Serve Solutions supplies 4-Aminopyridine with a purity of ≥99%. We do not represent this product as USP, BP, or EP grade; it is intended for research and laboratory use.
How should 4-Aminopyridine be handled safely?
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4-Aminopyridine is classified as acutely toxic (H300) and an irritant (H315, H319, H335). Handling requires appropriate personal protective equipment including a dust mask (N95/P2), eyeshields, face shields, and gloves. Work should be conducted in a well-ventilated area, and immediate medical attention is required in case of exposure.
Is 4-Aminopyridine a controlled substance?
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The provided data does not indicate that 4-Aminopyridine is a controlled substance. However, users should verify local regulations.
How is 4-Aminopyridine packed and shipped?
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4-Aminopyridine is shipped according to UN 2671 regulations for toxic substances (Class 6.1, Packing Group II). Detailed packing and shipping information for export can be provided upon request.
How can I request a sample or quote for 4-Aminopyridine?
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To request a sample or obtain a quotation for 4-Aminopyridine, please contact the Tech Serve Solutions sales team via our website or designated contact channels.
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