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(R)-(+)-1-Benzyl-3-acetylaminopyrrolidine

CAS 114636-33-8C13H18N2OChemical Synthesis

(R)-(+)-1-Benzyl-3-acetylaminopyrrolidine (CAS: 114636-33-8) is a chiral pyrrolidine derivative with the molecular formula C13H18N2O and a molecular weight of 218.29 g/mol. This compound serves as a valuable building block in asymmetric synthesis and organic chemistry. It is frequently employed in the preparation of complex chiral molecules and pharmaceutical intermediates, owing to its defined stereochemistry.

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(R)-(+)-1-Benzyl-3-acetylaminopyrrolidine (C13H18N2O) — chemical structure, CAS 114636-33-8; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral Building BlocksHeterocyclic Building BlocksPyrrolidines
01 /Applications

Chiral Building Block in Asymmetric Synthesis

This compound is extensively used as a chiral auxiliary or synthon in asymmetric synthesis. Its defined stereochemistry allows for the stereoselective construction of complex organic molecules, including pharmaceutical intermediates.

Intermediate in Pharmaceutical Synthesis

The pyrrolidine core and chiral nature make (R)-(+)-1-Benzyl-3-acetylaminopyrrolidine a key intermediate in the synthesis of various pharmacologically active compounds. It can be incorporated into drug candidates targeting diverse therapeutic areas.

Reagent in Heterocyclic Chemistry

As a functionalised heterocyclic compound, it finds application in reactions that build or modify heterocyclic ring systems. These structures are prevalent in many natural products and synthetic drugs.

02 /Properties
Molecular weight218.29
Empirical formulaC13H18N2O
Assay97%
Boiling point307-308 °C/760 mmHg(lit.)
Density1.139 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.5470(lit.)
Optical activity[α]20/D +24 in 1% chloroform
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Flash point>110 °C / >230 °F
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
114636-33-8
MDL number
MFCD04974061
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (R)-(+)-1-Benzyl-3-acetylaminopyrrolidine used for?

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(R)-(+)-1-Benzyl-3-acetylaminopyrrolidine is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the preparation of complex organic molecules and pharmaceutical compounds.

What are the CAS number and formula for (R)-(+)-1-Benzyl-3-acetylaminopyrrolidine?

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The CAS number for (R)-(+)-1-Benzyl-3-acetylaminopyrrolidine is 114636-33-8, and its empirical formula is C13H18N2O.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (R)-(+)-1-Benzyl-3-acetylaminopyrrolidine with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the specifications.

How should (R)-(+)-1-Benzyl-3-acetylaminopyrrolidine be handled?

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This compound is a Warning substance (GHS07) and may cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation.

Is (R)-(+)-1-Benzyl-3-acetylaminopyrrolidine a controlled substance?

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The provided data does not indicate that (R)-(+)-1-Benzyl-3-acetylaminopyrrolidine is a controlled substance.

How is (R)-(+)-1-Benzyl-3-acetylaminopyrrolidine packed and exported?

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Tech Serve Solutions can export chemicals globally. Packaging details will be provided upon request, adhering to all relevant shipping regulations.

How can I request a sample or quote for (R)-(+)-1-Benzyl-3-acetylaminopyrrolidine?

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Please contact our sales team or use the online inquiry form to request a sample or a quote for (R)-(+)-1-Benzyl-3-acetylaminopyrrolidine.

Need (R)-(+)-1-Benzyl-3-acetylaminopyrrolidine in a specific grade or volume?