(R)-(+)-1-Amino-2-(methoxymethyl)pyrrolidine
(R)-(+)-1-Amino-2-(methoxymethyl)pyrrolidine (CAS: 72748-99-3; Formula: C6H14N2O) is a chiral building block with a molecular weight of 130.19 g/mol. This optically active amine, with a specific rotation of [α]18/D +79°, is a valuable reagent primarily utilised in asymmetric synthesis. It plays a role in the creation of complex chiral molecules for various chemical research and development applications.
- IUPAC
- (R)-1-Amino-2-(methoxymethyl)pyrrolidine,RAMP
Asymmetric Synthesis Reagent
Serves as a crucial chiral auxiliary or building block in asymmetric synthesis, enabling the stereoselective construction of complex organic molecules. Its unique structure facilitates the introduction of chirality into target compounds.
Chiral Building Block
Used as a versatile chiral intermediate in the synthesis of pharmaceuticals and other fine chemicals. Its pyrrolidine core and functional groups allow for diverse chemical transformations.
Heterocyclic Chemistry
Incorporated into synthetic strategies involving heterocyclic compounds. The pyrrolidine ring structure makes it a useful component for constructing novel heterocyclic systems.
| Molecular weight | 130.19 |
|---|---|
| Empirical formula | C6H14N2O |
| Assay | 96% |
| Boiling point | 42 °C/1.8 mmHg(lit.) |
| Density | 0.97 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.465(lit.) |
| Optical activity | [α]18/D +79°, neat |
| Optical purity | ee: 98% (GLC) |
| Application | Reagent for asymmetric synthesis. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 72 °C / 161.6 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-1-Amino-2-(methoxymethyl)pyrrolidine used for?
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This compound is primarily used as a reagent in asymmetric synthesis and as a chiral building block in organic synthesis, particularly for creating complex chiral molecules.
What are the CAS number and formula for this chemical?
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The CAS number is 72748-99-3 and the empirical formula (Hill notation) is C6H14N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-1-Amino-2-(methoxymethyl)pyrrolidine with an assay of 96% and optical purity of ee: 98%. This is a research or technical grade material and is not represented as USP, BP, or EP.
How should (R)-(+)-1-Amino-2-(methoxymethyl)pyrrolidine be handled?
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It is classified as a Warning, with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment such as eyeshields, gloves, and suitable respiratory protection should be used when handling.
Is (R)-(+)-1-Amino-2-(methoxymethyl)pyrrolidine a controlled substance?
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Based on the provided data, there is no indication that this compound is a controlled substance.
How is this product packed, shipped, and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, capable of handling export requirements for this product.
How can I request a quote or sample?
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Please contact the TSS sales team directly via our website or your dedicated account manager to request a quote or sample.
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