4-Iodo-L-phenylalanine
4-Iodo-L-phenylalanine (CAS: 24250-85-9), with the molecular formula C9H10INO2 and a molecular weight of 291.09 g/mol, is an unnatural amino acid derivative. It is a crucial building block in chemical biology and peptide chemistry, enabling the synthesis of modified peptides and proteins. Its iodinated phenyl ring offers a unique handle for further chemical modifications and studies in areas like biochemical research and drug discovery.
- IUPAC
- (S)-2-Amino-3-(4-iodophenyl)propanoic acid
Peptide Synthesis
4-Iodo-L-phenylalanine serves as a modified amino acid for incorporation into peptides. The iodine atom provides a site for subsequent cross-coupling reactions or radiolabelling.
Chemical Biology Research
This compound is utilised in studies of protein structure and function, particularly when probing protein-ligand interactions or developing new biochemical assays. Its unnatural structure allows for specific labelling or modification.
Drug Discovery and Development
As a phenylalanine derivative, it can be employed in the design and synthesis of peptidomimetics or small molecules targeting biological pathways. The iodo-substituent can influence binding affinity or serve as a point for further derivatisation.
Material Science
The unique properties conferred by the iodophenyl group may find applications in the development of novel materials or functionalised surfaces through controlled polymerisation or surface modification techniques.
| Molecular weight | 291.09 |
|---|---|
| Empirical formula | C9H10INO2 |
| Assay | ≥96.0% (HPLC) |
| Optical activity | [α]20/D −6.5±2°, c = 1% in acetic acid: water (4:1) |
| Storage temperature | −20°C |
| Impurities tested | ~1 mol/mol water |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Iodo-L-phenylalanine used for?
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4-Iodo-L-phenylalanine is primarily used in peptide synthesis, chemical biology research, and drug discovery as a modified amino acid and a building block for creating complex molecules.
What is the CAS number and molecular formula for 4-Iodo-L-phenylalanine?
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The CAS number is 24250-85-9 and the molecular formula is C9H10INO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Iodo-L-phenylalanine with an assay of ≥96.0% determined by HPLC. This product is intended for research and laboratory use and is not represented as USP, EP, BP, or pharmacopoeia grade.
How should 4-Iodo-L-phenylalanine be handled and stored?
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Handle 4-Iodo-L-phenylalanine with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It should be stored at −20°C.
Is 4-Iodo-L-phenylalanine a controlled substance?
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The provided data does not indicate that 4-Iodo-L-phenylalanine is a controlled substance.
How is 4-Iodo-L-phenylalanine packed, shipped, and exported?
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Tech Serve Solutions packs and ships chemicals in compliance with international regulations for safe transport. As a global supplier and exporter, we facilitate worldwide delivery of our products.
How can I request a sample or quote for 4-Iodo-L-phenylalanine?
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To request a sample or a quotation for 4-Iodo-L-phenylalanine, please contact our sales department through the website or by phone.
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