4,4′-Difluorobenzophenone
4,4′-Difluorobenzophenone (CAS: 345-92-6) is a fluorinated organic compound with the linear formula (FC 6 H 4 ) 2 CO and a molecular weight of 218.20 g/mol. This ketone serves as a valuable building block in organic synthesis. It has been specifically utilised in research concerning the thermal stability, water uptake, and proton conductivity of advanced membrane materials, demonstrating its importance in materials science research.
- Synonyms
- (FC6H4)2CO

Membrane Material Research
4,4′-Difluorobenzophenone has been employed in studies investigating the properties of carboxylated and sulfonated membranes. This research explores how the compound influences thermal stability, water absorption, and proton conductivity, crucial factors for membrane performance in various applications.
Organic Synthesis Intermediate
As a difluorinated benzophenone derivative, this compound functions as a key intermediate in the synthesis of more complex organic molecules. Its reactive carbonyl group and fluorinated phenyl rings offer versatility for various chemical transformations.
Materials Science Studies
The compound's specific structure lends itself to the development and characterisation of new materials. Its inclusion in membrane studies highlights its role in advancing the understanding of material behaviour under different conditions.
| Molecular weight | 218.20 |
|---|---|
| Linear formula | (FC6H4)2CO |
| Assay | 99% |
| Application | 4,4′-Difluorobenzophenone has been used in the study of thermal stability, water uptake and proton conductivity of carboxylated, carboxylated/sulfonated, and crosslinked membranes1. |
| Melting point | 102-105 °C(lit.) |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 152 °C / 305.6 °F |
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-36/37/38-51/53 |
| Safety statements (S) | 26-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4,4′-Difluorobenzophenone used for?
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4,4′-Difluorobenzophenone is primarily used as a building block in organic synthesis and has been utilised in research on the thermal stability, water uptake, and proton conductivity of membranes.
What is the CAS number and formula for 4,4′-Difluorobenzophenone?
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The CAS number is 345-92-6, and the linear formula is (FC 6 H 4 ) 2 CO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4,4′-Difluorobenzophenone with a minimum purity of 99%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated otherwise in the product specifications.
How should 4,4′-Difluorobenzophenone be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. It is harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation. It is also toxic to aquatic life with long-lasting effects.
How is 4,4′-Difluorobenzophenone packed and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures that 4,4′-Difluorobenzophenone is packed and shipped in compliance with all relevant international regulations for chemical transport.
How can I request a quote or sample?
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Please contact our sales department via the website or by telephone to request a quotation or a sample of 4,4′-Difluorobenzophenone.
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