4,4′-Difluorobenzil
4,4′-Difluorobenzil (CAS 579-39-5) is a fluorinated organic compound with the molecular formula C14H8F2O2 and a molecular weight of 246.21 g/mol. It presents as a useful building block in organic synthesis, particularly for the introduction of fluorinated aromatic moieties into more complex molecules. Its chemical structure, featuring two carbonyl groups and two fluorine atoms on phenyl rings, makes it a valuable intermediate in the development of advanced materials and bioactive compounds.
- Synonyms
- FC6H4COCOC6H4F

Organic Synthesis Intermediate
Utilised as a key building block in the synthesis of novel organic molecules. Its difluorinated benzil structure facilitates the creation of compounds with specific electronic and steric properties.
Pharmaceutical Research
Serves as a precursor or intermediate in the research and development of potential pharmaceutical agents. The presence of fluorine can modulate pharmacokinetic and pharmacodynamic properties of drug candidates.
Material Science
Applicable in the development of advanced materials, such as polymers or liquid crystals, where the incorporation of fluorinated aromatic units can impart desirable thermal or optical characteristics.
| Molecular weight | 246.21 |
|---|---|
| Linear formula | FC6H4COCOC6H4F |
| Assay | 98% |
| Melting point | 120-122 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ACHE(43), BCHE(590), CES1(1066) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4,4′-Difluorobenzil used for?
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4,4′-Difluorobenzil is primarily used as a building block in organic synthesis, in pharmaceutical research, and in material science applications.
What are the CAS number and chemical formula for 4,4′-Difluorobenzil?
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The CAS number is 579-39-5 and the linear chemical formula is FC<sub>6</sub>H<sub>4</sub>COCOC<sub>6</sub>H<sub>4</sub>F.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4,4′-Difluorobenzil with a minimum purity of 98%. We do not represent this product as USP, BP, EP or other pharmacopoeia grades.
How should 4,4′-Difluorobenzil be handled safely?
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Handle 4,4′-Difluorobenzil with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation as it may cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335).
How is 4,4′-Difluorobenzil packed and shipped?
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Tech Serve Solutions packs and exports chemicals according to international shipping regulations. For specific packing details or export inquiries, please contact our sales team.
How can I request a sample or quote for 4,4′-Difluorobenzil?
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To request a sample or a quote for 4,4′-Difluorobenzil, please contact our dedicated sales department via the website or by phone.
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