(R)-(+)-1-(4-Bromophenyl)ethylamine
(R)-(+)-1-(4-Bromophenyl)ethylamine (CAS: 45791-36-4), with the molecular formula C8H10BrN and a molecular weight of 200.08 g/mol, is a chiral amine. It serves as a valuable building block in asymmetric synthesis and organic chemistry. Its chiral nature makes it particularly useful for the stereoselective preparation of complex molecules and for chiral resolution processes in research and development.
- IUPAC
- (R)-(+)-4-Bromo-α-methylbenzylamine
- Synonyms
- (R)-(+)-4-Bromo-α-methylbenzylamine
Chiral Building Block
Utilised in organic synthesis for the construction of stereochemically defined molecules. Its defined chirality allows for enantioselective reactions, crucial in pharmaceutical and fine chemical development.
Asymmetric Synthesis
Serves as a precursor or reagent in asymmetric synthesis, enabling the creation of specific enantiomers. This is vital for developing active pharmaceutical ingredients (APIs) and other chiral compounds.
Chiral Resolution Agent
Employed as a resolving agent to separate racemic mixtures into individual enantiomers. This process is fundamental in obtaining enantiomerically pure compounds for various applications.
Research and Development
A key intermediate in academic and industrial research laboratories exploring new synthetic routes and novel chemical entities. Its availability supports innovation in medicinal chemistry and materials science.
| Molecular weight | 200.08 |
|---|---|
| Empirical formula | C8H10BrN |
| Assay | ≥96.0% (sum of enantiomers, GC) |
| Density | 1.390 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.566 |
| Optical activity | [α]20/D +20.5±1°, c = 3% in methanol |
| Optical purity | enantiomeric excess: ≥98.5% |
Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 2735 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C,N |
| Risk statements (R) | 22-34-51/53 |
| Safety statements (S) | 26-28-36/37/39-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-1-(4-Bromophenyl)ethylamine used for?
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(R)-(+)-1-(4-Bromophenyl)ethylamine is primarily used as a chiral building block in asymmetric synthesis and as a chiral resolution agent for the preparation of enantiomerically pure compounds, particularly in pharmaceutical and fine chemical research and development.
What is the CAS number and chemical formula for (R)-(+)-1-(4-Bromophenyl)ethylamine?
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The CAS number is 45791-36-4, and the chemical formula is C8H10BrN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-1-(4-Bromophenyl)ethylamine with an assay of ≥96.0% (sum of enantiomers, GC) and an enantiomeric excess of ≥98.5%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How is (R)-(+)-1-(4-Bromophenyl)ethylamine handled and shipped?
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This compound is classified as Danger, corrosive and toxic to aquatic life. It requires careful handling with appropriate personal protective equipment, including gloves, goggles, and respiratory protection. It is shipped as a hazardous material according to UN 2735, Class 8, Packing Group 3.
Can I request a sample or quote for (R)-(+)-1-(4-Bromophenyl)ethylamine?
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Yes, to request a sample or obtain a quotation, please contact our sales team through the website or by phone. We ship globally and can accommodate your specific requirements.
What are the key safety hazards associated with this chemical?
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(R)-(+)-1-(4-Bromophenyl)ethylamine is hazardous, indicated by GHS05 (corrosion), GHS07 (harmful), and GHS09 (environmentally hazardous) symbols. It is harmful if swallowed (H302) and causes severe skin burns and eye damage (H314). It is also toxic to aquatic life with long-lasting effects (H411).
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