N-(5-Bromo-pyridin-3-yl)-2,2-dimethyl-propionamide
N-(5-Bromo-pyridin-3-yl)-2,2-dimethyl-propionamide (CAS 873302-39-7) is a halogenated heterocyclic building block with the molecular formula C10H13BrN2O and a molar mass of 257.13 g/mol. It is the pivaloyl (2,2-dimethylpropionamide) derivative of 3-amino-5-bromopyridine, pairing a reactive ring-bromide with a robust amide group. Tech Serve Solutions supplies it as a research and synthesis reagent for medicinal-chemistry and fine-chemical programmes building functionalised pyridine scaffolds.
- Synonyms
- N-(5-Bromo-pyridin-3-yl)-2,2-dimethyl-propionamideN-(5-Bromopyridin-3-yl)pivalamideN-(5-Bromo-3-pyridinyl)-2,2-dimethylpropanamide2,2-Dimethyl-N-(5-bromopyridin-3-yl)propanamideN-(5-Bromopyridin-3-yl)-2,2-dimethylpropanamideCAS 873302-39-7
Pyridine building block for synthesis
Serves as a versatile heterocyclic intermediate for assembling substituted pyridine scaffolds in medicinal-chemistry and fine-chemical research. The combination of a pyridine core, a ring-bromide and a protected amino position supports multi-step routes.
Cross-coupling substrate
The aryl bromide on the pyridine ring is a recognised handle for palladium-catalysed cross-coupling reactions such as Suzuki-Miyaura, Stille and Buchwald-Hartwig chemistry. This enables controlled carbon-carbon and carbon-nitrogen bond formation at the 5-position.
Protected amino-pyridine intermediate
The 2,2-dimethylpropionamide (pivalamide) group masks the 3-amino function of the pyridine as a stable amide. It can act as a protecting and directing group during downstream functionalisation and is removable under suitable conditions to reveal the free amine.
Halogenated heterocycle for library design
As a brominated pyridine, it is suited to exploratory and parallel synthesis where a single reactive halide allows rapid diversification. This makes it useful for discovery-stage analogue and library work.
| Molecular weight | 257.13 |
|---|---|
| Empirical formula | C10H13BrN2O |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(5-Bromo-pyridin-3-yl)-2,2-dimethyl-propionamide used for?
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It is used mainly as a building block and intermediate in organic and medicinal-chemistry synthesis. The pyridine ring-bromide is a handle for palladium-catalysed cross-coupling, while the pivalamide group protects the amino position, making the compound a convenient platform for preparing functionalised pyridine derivatives.
What is the CAS number and molecular formula of N-(5-Bromo-pyridin-3-yl)-2,2-dimethyl-propionamide?
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The CAS number is 873302-39-7. The molecular formula is C10H13BrN2O (Hill notation), corresponding to a molecular weight of 257.13 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research and synthesis-grade reagent suitable for laboratory and fine-chemical use. A specific assay is confirmed on the certificate of analysis for each batch; we do not represent it as a USP, BP or EP pharmacopoeial grade. Please request current specifications for your intended application.
How should N-(5-Bromo-pyridin-3-yl)-2,2-dimethyl-propionamide be handled and stored?
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Handle it as a laboratory chemical using good practice: work in a well-ventilated area or fume hood, wear suitable gloves, eye protection and a lab coat, and avoid the formation of dust, contact with skin and eyes, and inhalation. Store in a tightly closed container in a cool, dry place away from incompatible materials, and always consult the current Safety Data Sheet before use.
How is N-(5-Bromo-pyridin-3-yl)-2,2-dimethyl-propionamide packed, shipped and exported?
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It is packed in laboratory-appropriate containers with secure inner protection and tamper-evident seals, in pack sizes from gram quantities to bulk by request. Tech Serve Solutions exports worldwide with full documentation, including a certificate of analysis and Safety Data Sheet, and arranges compliant labelling and freight for your destination.
How do I request a sample or quote?
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Contact Tech Serve Solutions with the product name or CAS number 873302-39-7, your required quantity and your delivery country. We will confirm availability, current specifications, lead time and a formal quotation, and can provide a sample where appropriate.
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