N-(4-Methylpyridin-2-yl)acetamide
N-(4-Methylpyridin-2-yl)acetamide (CAS 5327-32-2; C8H10N2O; molar mass 150.18 g/mol) is an acetamido-substituted methylpyridine used as a heterocyclic building block in organic and medicinal chemistry. The molecule pairs an acetamide group with a 4-methylpyridine ring, giving a versatile, directing 2-aminopyridine derivative for synthesis. Tech Serve Solutions supplies it as a research-grade fine chemical to laboratories and manufacturers worldwide, with documentation and export-ready packing on request.
- Synonyms
- N-(4-Methylpyridin-2-yl)acetamide2-Acetamido-4-methylpyridineN-(4-Methyl-2-pyridyl)acetamide2-(Acetylamino)-4-methylpyridineAcetamide, N-(4-methyl-2-pyridinyl)-

Heterocyclic building block
Serves as a pyridine-based intermediate in multi-step organic synthesis, where the acetamido and methyl substituents provide defined sites for further functionalisation.
Pharmaceutical and agrochemical research
Used in medicinal- and discovery-chemistry programmes as a 2-acetamidopyridine scaffold for preparing more complex nitrogen heterocycles. Applications are general and depend on the customer's route.
Protected aminopyridine intermediate
The acetamide can act as a protected form of the corresponding 2-amino-4-methylpyridine, allowing selective chemistry before deprotection back to the free amine.
Directed C–H functionalisation studies
As an N-(pyridin-2-yl)acetamide, it is of interest in methodology work that exploits the amide nitrogen and ring nitrogen as coordinating or directing groups.
Laboratory reference and method development
Supplied as a defined single compound for use as a synthetic reagent and in analytical method development where a characterised pyridine derivative is required.
| Molecular weight | 150.18 |
|---|---|
| Empirical formula | C8H10N2O |
Precautionary statements
- P305IF IN EYES
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(4-Methylpyridin-2-yl)acetamide used for?
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It is used primarily as a heterocyclic building block and synthetic intermediate. The acetamido-methylpyridine structure makes it useful in pharmaceutical, agrochemical and general organic synthesis for constructing more complex pyridine-containing molecules. Specific end-uses depend on the customer's chemistry.
What is the CAS number and molecular formula of N-(4-Methylpyridin-2-yl)acetamide?
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Its CAS number is 5327-32-2 and its molecular formula is C8H10N2O (Hill notation), corresponding to a molecular weight of 150.18 g/mol. It is also described as 2-acetamido-4-methylpyridine.
What grade and purity does Tech Serve Solutions supply?
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We supply N-(4-Methylpyridin-2-yl)acetamide as a research- and technical-grade fine chemical for synthesis and laboratory use. We do not represent it as USP, BP or EP pharmacopoeial grade. A current specification and certificate of analysis can be provided with each batch on request.
What safety and handling precautions apply?
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Handle in accordance with good laboratory practice and the current Safety Data Sheet. The supplied precautionary guidance is P305 + P351 + P338: IF IN EYES, rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, and continue rinsing. Use appropriate eye protection and avoid contact with skin and eyes.
How is N-(4-Methylpyridin-2-yl)acetamide packed, shipped and exported?
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It is packed in sealed, appropriately labelled containers sized from research quantities to bulk, with packaging selected to protect product integrity. As an established exporter, Tech Serve Solutions arranges international shipment with the required documentation and an accompanying Safety Data Sheet.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, packing preference and destination, and we will respond with availability, lead time and a formal quotation. Reference the product name N-(4-Methylpyridin-2-yl)acetamide or CAS 5327-32-2 to speed handling.
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