(1S)-(+)-2-Azabicyclo[2.2.1]hept-5-en-3-one

CAS 130931-83-8C6H7NOChemical Synthesis

(1S)-(+)-2-Azabicyclo[2.2.1]hept-5-en-3-one (CAS: 130931-83-8; Formula: C6H7NO; MW: 109.13) is a chiral lactam building block. It is primarily used as a precursor in the asymmetric synthesis of enantiomers of carbocyclic nucleosides, such as carbovir. This compound is offered by Tech Serve Solutions with an assay of ≥98% and high optical purity (ee: 99%).

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(1S)-(+)-2-Azabicyclo[2.2.1]hept-5-en-3-one (C6H7NO) — chemical structure, CAS 130931-83-8; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral Building BlocksLactamsOrganic Building Blocks

01 /Applications

Chiral Precursor for Carbocyclic Nucleosides

This lactam serves as a key intermediate in the synthesis of enantiomerically pure carbocyclic nucleosides. It is a precursor to the enantiomers of carbovir, which are important in antiviral research.

Asymmetric Synthesis

Utilised in asymmetric synthesis, this compound facilitates the stereoselective construction of complex organic molecules. Its defined stereochemistry is crucial for building chiral targets.

Organic Building Block

As a versatile organic building block, it is valuable in medicinal chemistry and organic synthesis for introducing specific structural motifs. Its bicyclic structure offers unique synthetic possibilities.

02 /Properties

Molecular weight	109.13
Empirical formula	C6H7NO
Assay	≥98%
Optical activity	[α]20/D +565°, c = 1 in chloroform
Optical purity	ee: 99% (HPLC)
Application	This lactam and its antipode are precursors to the enantiomers of the carbocyclic nucleoside carbovir.
Melting point	94-97 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

130931-83-8

MDL number

MFCD00211275

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (1S)-(+)-2-Azabicyclo[2.2.1]hept-5-en-3-one used for?

(1S)-(+)-2-Azabicyclo[2.2.1]hept-5-en-3-one is used as a chiral precursor in the asymmetric synthesis of enantiomers of carbocyclic nucleosides, such as carbovir.

What are the CAS number and chemical formula for this compound?

The CAS number is 130931-83-8 and the chemical formula is C6H7NO.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this compound with an assay of ≥98% and an optical purity of ee: 99% (HPLC). It is not supplied as USP, BP, or EP grade.

How should (1S)-(+)-2-Azabicyclo[2.2.1]hept-5-en-3-one be handled safely?

This compound is a warning irritant (H315, H319, H335) and requires appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Handle in a well-ventilated area.

How are your chemicals packed and shipped?

Tech Serve Solutions securely packs and exports fine chemicals globally, adhering to international shipping regulations for chemical substances. Specific packaging details can be provided upon request.

How can I request a sample or quote for (1S)-(+)-2-Azabicyclo[2.2.1]hept-5-en-3-one?

To request a sample or a quote, please contact our sales department through the website or call us directly. Our team will assist you with your inquiry.