(1S)-(+)-10-Camphorsulfonyl chloride
(1S)-(+)-10-Camphorsulfonyl chloride (CAS: 21286-54-4, C10H15ClO3S) is a chiral sulphonyl chloride compound with a molecular weight of 250.74 g/mol. It functions as a valuable chiral resolving agent, essential in asymmetric synthesis for separating enantiomers. This compound also finds application in the synthesis of specific organic molecules, contributing to the development of new chemical entities.
- IUPAC
- (+)-Camphor-10-sulfonyl chloride,(1S)-Camphor-10-sulfonic acid chloride

Chiral Resolving Agent
As a chiral resolving agent, (1S)-(+)-10-Camphorsulfonyl chloride is employed to separate racemic mixtures into their individual enantiomers. This is a critical step in the production of enantiomerically pure compounds for various chemical and pharmaceutical applications.
Asymmetric Synthesis
This compound serves as a key building block or auxiliary in asymmetric synthesis. Its inherent chirality allows for the stereoselective construction of complex molecules, enabling the creation of specific stereoisomers.
Synthesis of Oxytocin Antagonists
It has been utilised in the synthesis of nonpeptide oxytocin antagonists. This application highlights its role in medicinal chemistry research and development for potential therapeutic agents.
| Molecular weight | 250.74 |
|---|---|
| Empirical formula | C10H15ClO3S |
| Assay | 97% |
| Optical activity | [α]22/D +33°, c = 1 in chloroform |
| Application | Chiral resolving agent.1 Used in the synthesis of nonpeptide oxytocin antagonists.2 |
| Melting point | 65-67 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1S)-(+)-10-Camphorsulfonyl chloride used for?
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(1S)-(+)-10-Camphorsulfonyl chloride is primarily used as a chiral resolving agent in asymmetric synthesis and in the synthesis of specific organic compounds such as nonpeptide oxytocin antagonists.
What are the CAS number and molecular formula for (1S)-(+)-10-Camphorsulfonyl chloride?
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The CAS number for (1S)-(+)-10-Camphorsulfonyl chloride is 21286-54-4, and its molecular formula is C10H15ClO3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (1S)-(+)-10-Camphorsulfonyl chloride with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should (1S)-(+)-10-Camphorsulfonyl chloride be handled safely?
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This compound causes severe skin burns and eye damage. Handling requires appropriate personal protective equipment, including eyeshields, a face shield, chemical-resistant gloves, and respiratory protection. Work in a well-ventilated area or fume hood and avoid contact with skin, eyes, and clothing.
Is (1S)-(+)-10-Camphorsulfonyl chloride available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (1S)-(+)-10-Camphorsulfonyl chloride, serving customers worldwide.
How can I request a sample or quote for (1S)-(+)-10-Camphorsulfonyl chloride?
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To request a sample or a quotation, please contact our sales department through the website or by phone, providing your details and the product information.
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