N-(4-tert-Butylsulfanyl-pyridin-3-yl)-2,2-dimethyl-propionamide
N-(4-tert-Butylsulfanyl-pyridin-3-yl)-2,2-dimethyl-propionamide (CAS 766557-58-8; C14H22N2OS; molar mass 266.40 g/mol) is a heterocyclic building block built on a 3-aminopyridine core. It pairs a tert-butylthio (tert-butylsulfanyl) group at the 4-position with a pivaloyl amide (2,2-dimethylpropionamide) at the 3-amino nitrogen. This functionalised pyridine is used in chemical synthesis and medicinal-chemistry research as an intermediate and scaffold for further elaboration. Tech Serve Solutions supplies it as a research-grade material to laboratory and process-development customers worldwide.
- Synonyms
- N-(4-tert-Butylsulfanyl-pyridin-3-yl)-2,2-dimethyl-propionamideN-(4-(tert-butylthio)pyridin-3-yl)pivalamideN-[4-(tert-butylsulfanyl)pyridin-3-yl]-2,2-dimethylpropanamideN-[4-(tert-butylthio)-3-pyridyl]-2,2-dimethylpropanamideCAS 766557-58-8C14H22N2OS
Heterocyclic building block
Serves as a pyridine-based building block for the assembly of more complex nitrogen heterocycles. The pre-installed substitution pattern at the 3- and 4-positions provides a defined platform for downstream chemical synthesis.
Pharmaceutical and medicinal-chemistry research
Functionalised aminopyridines of this type are widely employed as intermediates and scaffolds in early-stage drug-discovery and structure-activity studies. It is offered for research and development use, not for clinical or therapeutic application.
Protected amine handle (pivalamide)
The 2,2-dimethylpropionamide (pivaloyl) group is a robust amide that masks the pyridyl amine and is a classic directing group in directed ortho-metalation chemistry. It allows controlled further functionalisation and can be removed under suitable conditions to reveal the free amine.
Protected thiol equivalent (tert-butylthio)
The tert-butylsulfanyl substituent acts as a stable, masked thiol handle on the pyridine ring. It can be carried through multi-step sequences and later transformed, supporting the synthesis of sulfur-containing targets.
Reference and analytical use
As a defined single compound with a known CAS number and molecular formula, it can be used as a characterised reference material in method development and analytical work.
| Molecular weight | 266.40 |
|---|---|
| Empirical formula | C14H22N2OS |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(4-tert-Butylsulfanyl-pyridin-3-yl)-2,2-dimethyl-propionamide used for?
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It is used primarily as a heterocyclic building block and synthetic intermediate. The pyridine scaffold, with its tert-butylthio and pivaloyl-amide groups, is a useful platform in chemical synthesis and medicinal-chemistry research for preparing more complex molecules. It is supplied for research and development purposes only.
What is the CAS number and molecular formula of N-(4-tert-Butylsulfanyl-pyridin-3-yl)-2,2-dimethyl-propionamide?
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The CAS number is 766557-58-8 and the empirical formula is C14H22N2OS (Hill notation), corresponding to a molecular weight of 266.40 g/mol.
What grade and purity does Tech Serve Solutions supply?
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We supply this compound as a research/technical-grade building block for laboratory and process-development use. We do not represent it as USP, BP or EP pharmacopoeial grade. A current specification and certificate of analysis, including the assay for the available lot, are provided on request and accompany each consignment.
What safety and handling precautions apply?
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Treat it as a research chemical: handle only in a properly equipped laboratory with suitable ventilation, gloves, eye protection and a lab coat, and avoid generating dust, contact and ingestion. A formal GHS classification is not included in the data we hold for this item, so confirm hazards against the Safety Data Sheet supplied with each shipment before use.
How is N-(4-tert-Butylsulfanyl-pyridin-3-yl)-2,2-dimethyl-propionamide packed, shipped and exported?
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It is packed in sealed, appropriately labelled containers sized to the order, from gram quantities to larger research scales, with a certificate of analysis. Tech Serve Solutions exports worldwide and prepares the documentation and transport arrangements required for compliant international dispatch.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, packaging and destination, quoting CAS 766557-58-8. We will respond with current availability, lead time and a formal quotation, and can arrange a sample where appropriate.
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