N-(5-Hydroxy-pyridin-2-yl)-2,2-dimethyl-propionamide
N-(5-Hydroxy-pyridin-2-yl)-2,2-dimethyl-propionamide (CAS 898561-65-4; molecular formula C10H14N2O2; molar mass 194.23 g/mol) is a substituted pyridine building block in which a pivalamide group and a free hydroxyl are placed on the pyridine ring. The pivaloyl moiety serves as a robust amine-protecting group, while the phenolic-type hydroxyl offers a further site for functionalisation. Tech Serve Solutions supplies it as a research-grade heterocyclic intermediate for synthetic and medicinal chemistry.
- Synonyms
- N-(5-Hydroxy-pyridin-2-yl)-2,2-dimethyl-propionamideN-(5-Hydroxypyridin-2-yl)pivalamideN-(5-hydroxy-2-pyridinyl)-2,2-dimethylpropanamide2,2-Dimethyl-N-(5-hydroxypyridin-2-yl)propanamideCAS 898561-65-4C10H14N2O2
Heterocyclic building block
Used as a functionalised pyridine scaffold in multistep organic synthesis. The combination of a protected amine and a free hydroxyl allows selective, sequential elaboration of the ring.
Pharmaceutical and agrochemical intermediate
Serves as an intermediate in the preparation of more complex pyridine-containing molecules of interest in medicinal and agrochemical research programmes.
Pivaloyl-protected amine handle
The 2,2-dimethyl-propionamide (pivalamide) group provides a sterically hindered, hydrolytically stable protecting group for the ring amine, enabling chemistry to be directed to other positions.
Site for O-functionalisation
The 5-hydroxy group offers a convenient point for etherification, acylation or cross-coupling, supporting the construction of structurally diverse pyridine derivatives.
Discovery and laboratory research
Supplied for use in research and development, method development and structure-activity studies where a defined pyridine intermediate is required.
| Molecular weight | 194.23 |
|---|---|
| Empirical formula | C10H14N2O2 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(5-Hydroxy-pyridin-2-yl)-2,2-dimethyl-propionamide used for?
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It is used mainly as a heterocyclic building block and synthetic intermediate. The protected amine and free hydroxyl on the pyridine ring make it a versatile scaffold for medicinal chemistry, agrochemical research and general organic synthesis.
What is the CAS number and molecular formula of N-(5-Hydroxy-pyridin-2-yl)-2,2-dimethyl-propionamide?
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Its CAS number is 898561-65-4 and its molecular formula is C10H14N2O2, corresponding to a molecular weight of 194.23 g/mol (Hill notation).
What grade and purity does Tech Serve Solutions supply?
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We supply this compound as a research/technical-grade heterocyclic building block. A current Certificate of Analysis stating the actual assay for each batch is provided on request. We do not represent it as USP, BP or EP pharmacopoeial grade.
How should N-(5-Hydroxy-pyridin-2-yl)-2,2-dimethyl-propionamide be handled and stored?
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Handle it as a laboratory research chemical, using good laboratory practice: appropriate gloves and eye protection, adequate ventilation and avoidance of dust formation. Store in a tightly closed container in a cool, dry, well-ventilated place away from incompatible materials. A Safety Data Sheet accompanies every shipment and should be reviewed before use.
How is N-(5-Hydroxy-pyridin-2-yl)-2,2-dimethyl-propionamide packed, shipped and exported?
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It is packed in laboratory-appropriate containers, from gram quantities to larger research volumes, with secure inner and outer packaging and full labelling. As a specialist exporter since 1998, Tech Serve Solutions ships worldwide with the relevant documentation and Safety Data Sheet included.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, packaging and destination, quoting CAS 898561-65-4. We will respond with availability, lead time, a Certificate of Analysis and a formal quotation.
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