N-(5-Hydroxymethyl-pyridin-2-yl)-2,2-dimethyl-propionamide
N-(5-Hydroxymethyl-pyridin-2-yl)-2,2-dimethyl-propionamide (CAS 882016-49-1) is a pyridine-based heterocyclic building block with the empirical formula C11H16N2O2 and a molecular weight of 208.26 g/mol. It pairs a pivalamide-protected 2-aminopyridine with a free hydroxymethyl handle, making it a versatile intermediate for chemical synthesis. Tech Serve Solutions supplies this compound to research, discovery and process-development laboratories worldwide as a research-grade fine chemical.
- Synonyms
- N-(5-Hydroxymethyl-pyridin-2-yl)-2,2-dimethyl-propionamideN-[5-(Hydroxymethyl)pyridin-2-yl]-2,2-dimethylpropanamideN-[5-(hydroxymethyl)-2-pyridinyl]-2,2-dimethylpropanamide2,2-Dimethyl-N-[5-(hydroxymethyl)pyridin-2-yl]propanamideCAS 882016-49-1C11H16N2O2
Heterocyclic building block
Serves as a functionalised pyridine scaffold in multi-step organic synthesis. The combination of an amide-protected aminopyridine and a primary alcohol allows selective, sequential transformations on a single core.
Pharmaceutical and discovery intermediate
Used as an intermediate in medicinal-chemistry and drug-discovery programmes where substituted aminopyridine motifs are required. It supports library synthesis and structure-activity exploration around the pyridine ring.
Hydroxymethyl handle for further functionalisation
The free benzylic-type hydroxymethyl group can be oxidised, halogenated, esterified or otherwise derivatised, enabling onward coupling and elaboration of the molecule.
Protected aminopyridine reagent
The 2,2-dimethylpropanamide (pivaloyl) group acts as a robust protecting and directing group on the pyridin-2-amine nitrogen, useful in regioselective synthetic routes.
Laboratory reference and research material
Supplied for use in method development, analytical reference work and exploratory chemistry within professional laboratory settings.
| Molecular weight | 208.26 |
|---|---|
| Empirical formula | C11H16N2O2 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(5-Hydroxymethyl-pyridin-2-yl)-2,2-dimethyl-propionamide used for?
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It is used primarily as a heterocyclic building block and synthetic intermediate. The pivalamide-protected aminopyridine core and the free hydroxymethyl group make it useful in pharmaceutical, discovery and general organic synthesis where a functionalised pyridine scaffold is needed.
What is the CAS number and molecular formula of N-(5-Hydroxymethyl-pyridin-2-yl)-2,2-dimethyl-propionamide?
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The CAS number is 882016-49-1. The empirical formula in Hill notation is C11H16N2O2, with a molecular weight of 208.26 g/mol.
What grade and purity does Tech Serve Solutions supply?
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We supply this compound as a research/technical-grade fine chemical for laboratory and synthetic use. We do not represent it as USP, BP or EP pharmacopoeia grade. Specific assay values and a certificate of analysis for the available lot can be confirmed at the time of enquiry.
How should N-(5-Hydroxymethyl-pyridin-2-yl)-2,2-dimethyl-propionamide be handled and stored?
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No specific GHS hazard classification is provided in our product data for this item. As a general precaution, handle it as a research chemical of undetermined hazard: use appropriate personal protective equipment, avoid dust, skin and eye contact and inhalation, work in a well-ventilated area, and store it tightly closed in a cool, dry place. Always confirm the current safety data sheet before use.
How is N-(5-Hydroxymethyl-pyridin-2-yl)-2,2-dimethyl-propionamide packed, shipped and exported?
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It is packed in sealed, labelled laboratory containers appropriate to the order quantity, from gram to larger research scales. Tech Serve Solutions arranges documentation and compliant international shipping, and packaging or pack sizes can be tailored on request.
How do I request a sample or quote?
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Contact Tech Serve Solutions with the product name or CAS 882016-49-1 and your required quantity. We will confirm current availability, lot details and lead time, and provide a quotation for your sample or order.
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